International Point Prevalence Study of Intensive Care Unit Transfusion Practices
Completed
- Conditions
- All patients = 18 years admitted to the adult Intensive Care Unit.
- Registration Number
- NL-OMON28052
- Lead Sponsor
- AMC
- Brief Summary
DOI: 10.1016/j.tracli.2019.09.002
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- Not specified
- Target Recruitment
- 3000
Inclusion Criteria
Patients are included in the study if they are aged 18 years and older and are newly admitted to the ICU during the course of a pre-specified week (7 days).
Exclusion Criteria
All patients younger than 18 years old
No informed consent in countries where no opt-out procedure applies.
Study & Design
- Study Type
- Observational non invasive
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Our objective is to quantify international transfusion practice in ICUs. We will be looking at transfusion and administration of RBCs, platelets, plasma and several coagulation agents (pro-coagulant and anti-fibrinolytic) in correlation to clinical parameters and corresponding laboratory values. Differences within and between regions will be studied.
- Secondary Outcome Measures
Name Time Method Secondary objectives will include the following: <br>-To evaluate the effect of physiological triggers on transfusion practice; <br>-To evaluate the effect of transfusion on corresponding hematology laboratory variables; <br>-To compare transfusion practice in different patient subgroups, e.g. septic shock and coronary disease; <br>-To evaluate the association of transfusion thresholds applied and clinical outcomes (e.g. 28-day mortality).<br>