Cumulative effects of transcranial direct current stimulation on meth craving
- Conditions
- Methamphetamine dependency.Dependence syndrom, Mental and behavioural disorders due to use of other stimulants, including methamphethamine
- Registration Number
- IRCT2014031611234N2
- Lead Sponsor
- Cognitive Sciences and Technology Council
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete
- Sex
- Male
- Target Recruitment
- 180
Inclusion criteria are: (1) the methamphetamine dependents being referred for treatment to Vardij Therapeutic Community Residential Center which is a specialized center for stimulants; (2) a history of at least 12 months of meth dependence (moderate or severe) based on DSM-V criteria before receiving treatment; (3) Being in the age range of 18-50; (4) being abstinence from any drugs except cigarettes, for at least a week prior to the experiment, confirmed by urine analysis inside the residential centre; (5) A history of meth using at least 6 days a week in the month before entering the treatment. (6) Being able to provide informed, written consent. Exclusion criteria include: (1) any current major psychiatric disorders (2) Moderate to severe traumatic brain injury with evidence of neurological deficits, neurological disorders, or severe or unstable medical conditions that might be compromised by participation in the study; (3) having intracranial metal implantation.
Not provided
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Immediate meth craving. Timepoint: Pre & Post brain stimulation. Method of measurement: visual-analogue scale(VAS).;Basic meth craving. Timepoint: Pre & Post brain stimulation. Method of measurement: Desires for Drug Questionnaire Adapted for Meth (DDQ).;Cue-induced craving. Timepoint: Pre & Post brain stimulation. Method of measurement: Computerized cue-induced craving assessment task (CICT).
- Secondary Outcome Measures
Name Time Method Mood state. Timepoint: Pre and Post brain stimulation. Method of measurement: Positive and Negative Affect (PANAS) questionnaire.