Effects of Q10 supplementation in type II diabetes
Phase 2
- Conditions
- Type 2 diabetic.Non-insulin-dependent diabetes mellitus
- Registration Number
- IRCT2016081525949N3
- Lead Sponsor
- Vice Chancellor for research of Arak University of Medical Sciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete
- Sex
- Female
- Target Recruitment
- 68
Inclusion Criteria
Patients that have been suffered type 2 diabetes for more than 2 years and that have not consumed vitamin and mineral supplements during the last three months. Exclusion criteria: changing in dosage of glucose lowering medications, physical activity and diet during the intervention; any chronic renal, hepatic, thyroid, haematic and gastrointestinal disorders; hormone therapy; insulin therapy; alcoholism; smoking; pregnancy; lactation and using anticoagulants, diuretics and ß blockers.
Exclusion Criteria
Not provided
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Fasting glucose. Timepoint: Before and after 12 weeks of intervention. Method of measurement: Colorimetric.;HbA1C. Timepoint: Before and after 12 weeks of intervention. Method of measurement: Chromatoghraphy.;Fasting insulin. Timepoint: Before and after 12 weeks of intervention. Method of measurement: ELISA.;Coenzyme Q10. Timepoint: Before and after 12 weeks of intervention. Method of measurement: Chromatoghraphy.;Leptin. Timepoint: Before and after 12 weeks of intervention. Method of measurement: ELISA.;Adiponectin. Timepoint: Before and after 12 weeks of intervention. Method of measurement: ELISA.;8-isoprostane. Timepoint: Before and after 12 weeks of intervention. Method of measurement: ELISA.;Malondialdehyde. Timepoint: Before and after 12 weeks of intervention. Method of measurement: Spectrophotometric.
- Secondary Outcome Measures
Name Time Method BMI. Timepoint: Before and after 12 weeks of intervention. Method of measurement: Formula.