The effectiveness of intravenous dexmeditomidine versus lignocaine on perioperative haemodynamics in patients undergoing laparoscopic cholecystectomy
Phase 4
Not yet recruiting
- Conditions
- Acute cholecystitis. Ayurveda Condition: NOT APPLICABLE,
- Registration Number
- CTRI/2021/07/034595
- Lead Sponsor
- NOT APPLICABLE
- Brief Summary
To study the haemodynamic response to pneumo peritonium while administering infusions of either dexmeditomidine or lignocaine.dexmeditomidine blunts the hemodynamic response to pneumo peritoneum.lignocaine decreases post operative pain.to compare these drugs and their hemodynamic responses
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Not Yet Recruiting
- Sex
- All
- Target Recruitment
- 60
Inclusion Criteria
- American Society of Anaesthesiologists physical status I,II,III 2)Patients with age :20 TO 60 Years.
-
- BMI ≤30 kg/m2 4)Patients undergoing elective laparoscopic cholecystectomy (non malignant) .
Exclusion Criteria
- 1)Patients refusal 2)Patients with uncontrolled cardio respiratory, renal, hepatic or endocrine disease 3)Conversion of laparoscopic to open cholecystectomy 4)Patients with drains placed insitu.
- 5)Patients who are unable to perform VAS scale.
- 6)Surgical time exceeding 150 min.
- 7)Pregnant and lactating women.
- 8)Patients who are on Beta adrenergic blocker therapy.
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method To study the attenuation of blood pressure and heart rate response to pneumo peritoneum in patients undergoing laparoscopic cholecystectomy the first requirement of analgesic dose within 24 hours
- Secondary Outcome Measures
Name Time Method To compare the post operative sedation score between two groups To assess and compare the Time to first request for analgesia post operatively.-defined as whenever the patient complains of pain or when visual analogue score
Trial Locations
- Locations (1)
SRI VENKATESWARA INSTITUTE OF MEDICAL SCIENCES
🇮🇳Chittoor, ANDHRA PRADESH, India
SRI VENKATESWARA INSTITUTE OF MEDICAL SCIENCES🇮🇳Chittoor, ANDHRA PRADESH, IndiaManjusreePrincipal investigator8886946282manjuyashu1492@gmail.com