Effects of discontinuation of long-term benzodiazepine use on cognitive function in schizophrenia - Effects of discontinuation of benzodiazepine on cognitive function in schizophrenia (BZD discontinuation study)

Department of Neuropsychiatry St. Marianna University School of Medicine0 个研究点目标入组 60 人开始时间: 2010年9月1日最近更新: 2023年10月17日

适应症

试验速览

阶段: 未知
状态: 已完成
发起方
入组人数: 60

研究概览入排标准研究者记录与标识符相似试验

研究概览

简要总结

BZDs were reduced or discontinued safely in most patients, and no emergent withdrawal symptoms were observed. Significant improvements were shown in verbal memory, working memory, and composite score, as measured by the BACS-J without practice effects. In addition, the motivation/energy score on the SQLS-J, the negative symptoms and total scores on the PANSS significantly improved after tapering BZDs.

研究设计

研究类型: Interventional

入排标准

年龄范围: 18years-old 至 59years-old（—）
性别: All

入选标准

未提供

排除标准

•1) comorbid central nervous system disorder 2) meeting DSM-IV-TR criteria for alcohol or other substance dependence 3) meeting DSM-IV-TR criteria for mental retardation 4) taking tricyclic antidepressants 5) treatment with electroconvulsive therapy in the 3 months preceding the study; and 6) inability to understand the study protocol

研究者

发起方

Department of Neuropsychiatry St. Marianna University School of Medicine

相似试验

已完成

不适用

Telepsychology for Benzodiazepines Withdrawal in Adults Suffering From Hypnotic-dependent InsomniaChronic InsomniaHypnotic Dependence

NCT04751851Association Nationale de Promotion des Connaissances sur le Sommeil128

已完成

4 期

Effects of Discontinuation of Benzodiazepine-derivative Hypnotics on Cognitive and Motor Functions in Elderly PersonsAdverse Effects

NCT00707915Minamihanno Hospital30

已完成

不适用

Tapering Multiple Benzodiazepine Drugs study through investigating Cognition and Risk of Side Effects for Depressiodepression

JPRN-UMIN000026499Kansai medical university80

已完成

4 期

The effects of ceasing opioid, benzodiazepine, or Z-hypnotic drug use on measures of driving performance and postural balance.Pijnklachtenchronic pain1004099810002861Insomnia

NL-OMON44190niversiteit Maastricht94

进行中（未招募）

1 期

The effect of tappering off medications on driving performance and balance.

EUCTR2017-003365-99-NLMaastricht University108