Efficacy of nuclear medicine imaging to detect fibroblast activation protein in pancreatic and biliary tract cancer.
- Conditions
- Neoplasms
- Registration Number
- KCT0009207
- Lead Sponsor
- Seoul National University Hospital
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Active, not recruiting
- Sex
- All
- Target Recruitment
- 30
Adults over 20 years old
- Patients suspected of having pancreatic cancer or biliary tract cancer on imaging tests including CT and PET/CT and confirmed to have cancer on biopsy
- Patients in whom cancer was not confirmed on biopsy due to difficulty in histological examination before surgery, but surgical treatment was planned due to strong suspicion of cancer based on clinical picture and imaging examination
- Patients who can provide written consent and comply with the research requirements before starting to participate in the study.
- Patients who gave written consent to establish a Bio Repository for liver, biliary tract, and pancreatic tumor research (H-0901-010-267)
- Patients who are pregnant or lactating
- Patients with a history of clinically significant uncontrolled seizures, central nervous system disease, or mental illness that, in the opinion of the investigator, may interfere with or interfere with the subject's ability to understand the consent form.
- Subjects who develop uncontrolled severe infection or other uncontrolled serious comorbidities
- Patients who have undergone other major surgery within 4 weeks prior to the study or who have not fully recovered from the effects of major surgery.
Study & Design
- Study Type
- Interventional Study
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Differences in measured variables related to expression of cancer associated fibroblasts according to clinical characteristics and tumor stage (T-stage, N-stage)
- Secondary Outcome Measures
Name Time Method Verification of correlation between variables measured in CT, FDG PET, FAPI PET and quantitative indices of RNA and Protein obtained from postoperative tissues