A RANDOMISED CONTROLLED COMPARISON OF VAGINAL AND ORAL BROMOCRIPTINE IN THE MANAGEMENT OF HYPERPROLACTINEMIA AMONG WOMEN ATTENDING INFERTILITY CLINIC IN ABUTH.
Not Applicable
Recruiting
- Conditions
- Fertility-female
- Registration Number
- PACTR202105631565416
- Lead Sponsor
- Irshad Asma
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- Female
- Target Recruitment
- 64
Inclusion Criteria
This will include consenting and well-motivated infertile women with laboratory evidence of hyperprolactinemia who are ready to comply with study requirements (clinic visits, repeated blood collections, vaginal drug administrations and timely use of medications).
Exclusion Criteria
Women with space occupying lesions or other complications requiring urgent intervention, those with active genital tract infections or cancers, renal or hepatic insufficiency, those already on treatment at the time of the study, nonconsenting women and those with allergies to any component of the drugs will be excluded from the study.
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method 1.Percentage fall in serum prolactin levels during treatment in both arms of the study.<br>2.Unit drop in prolactin levels in both study groups.<br>3.Proportion of women who experience side-effects in both arms of the study.<br>
- Secondary Outcome Measures
Name Time Method 1.Proportion of women in both arms who achieve symptom relief following treatment.<br>2.Drug discontinuation rate in both groups.<br>