Investigation of the effect of Intense Pulsed Light therapy on the signs and symptoms of contact lens discomfort.

niversity of New South Wales0 个研究点目标入组 48 人开始时间: 2022年10月19日最近更新: 2022年10月24日

适应症

试验速览

暂无简介。

•Age of 18 years and above
•Willing to sign informed consent and comply with study schedule.
•Normal vision defined as a minimum of 20/40 best corrected visual acuity in each eye.
•Healthy ocular surface, defined as no fluorescein corneal staining of grade 2 or more after a single instillation of non-preserved fluorescein solution followed by examination 1 minute after installation, considering minimal staining of grade 1 as normal in contact lens wearers.
•Normal external ocular examination with no eyelid deformation
•Ability to cooperate with and undergo the required study procedures.
•Contact lens wearers who have worn lenses for at least 6 months, used contact lenses for 3 weeks before the evaluation visit and used these lenses at least four times a week. Contact lenses should have been worn on a daily wear modality, where the lenses are worn for at least of 6 hours per day and remove the lenses before sleep.
•Experience symptoms of contact lens discomfort (CLD), defined as CLDEQ-8 Questionnaire score more than 13.

•Any ocular or systemic disease that might influence the tear film
•All forms of conjunctivitis, including allergic conjunctivitis
•Any history of previous ocular surgery or trauma, including chalazion excision, oculoplastic
•History of eyelid and periorbital skin disease or allergies in the past 1 month.
•History of herpes zoster infection and any viral infection episode before.
•Pregnancy, breast feeding
•Skin cancer, user of photosensitive drugs /foods
•Dark or deeply pigmented skin (Skin Fitzpatrick scale V/VI), which can be prone skin
•damage, such as discoloration or scarring after IPL treatment.
•Current use of any prescription on nonprescription ocular or systemic medications, including antihistamines.
•Use of artificial tear preparations during the period 4 hours before all visits
•Use of any ocular ointment during the 3 days before any study visit.
•Have an history of epilepsy and migraine
•Have any history of previous IPL treatment for dry eye.

发起方