A Study to compare the effect of three drugs -Dexmedetomidine, Lidocaine and Fentanyl in increasing heart rate and blood pressure in response to Laryngoscopy and Intubation in patients undergoing Cardiac Surgery
- Conditions
- Medical and Surgical,
- Registration Number
- CTRI/2022/05/042885
- Lead Sponsor
- Department of Anaesthesiology
- Brief Summary
Laryngoscopy and endotracheal intubation are associated with various hemodynamic changes due to sympathetic stimulation and to attenuate these responses is a major challenge for the anaesthesiologist. Hence, this study is designed to compare effects of intravenous Dexmedetomidine, Lidocaine and Fentanyl in Attenuation of Hemodynamic Response of Laryngoscopy and Intubation in patients undergoing Cardiac surgery.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Not Yet Recruiting
- Sex
- All
- Target Recruitment
- 90
1.Informed Consent 2.Patients undergoing Elective Cardiac Surgery 3.Ejection Fraction >35% 4.ASA Grade 2 and 3 5.BMI<30.
1.Intubation Attempt lasting longer than 15s and any intubation related problem 2.Allergic Sensitivity to the research medications 3.Patients with hypotension(SBP<90 mmhg) 4.Bradycardia(HR<60/min) 5.Diabetes 6.Asthma 7.Pregnancy 8.Chronic Kidney and liver diseases 9.Long QT 10.Any Addiction.
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Heart Rate, Systolic Blood Pressure, Diastolic Blood Pressure, Mean Arterial Pressure Before Intubation and 1,3,5,10 and 15 minutes post intubation
- Secondary Outcome Measures
Name Time Method Percentage of cases who experience side effects or complications(if any) 24 hours postoperation
Trial Locations
- Locations (1)
S.M.S Medical College Hospital
🇮🇳Jaipur, RAJASTHAN, India
S.M.S Medical College Hospital🇮🇳Jaipur, RAJASTHAN, IndiaDr Indu VermaPrincipal investigator9413622967dr.induverma@gmail.com