How special instrument affects placing implants in people with and without diabetics.

Not yet recruiting

Brief Summary: Patients reporting to the Department of Periodontics and Implantology, Vishnu Dental College with missing maxillary posterior teeth of nondiabetic patients and controlled type II diabetic patients will be included in the study as control and test group respectively. A written informed consent will be obtained from all the patients .Implant placement will be done using Piezosurgery . Subgingival plaque and crevicular fluid sample will be collected. Implant stability, Peri implant marginal bone changes, mean bone density measured at baseline and 6months. Molecular parameters like RANKL OPG will be assessed at baseline,1month and 3 months. Microbiological parameters will be assessed at baseline and 1 month.

Recruitment & Eligibility

Inclusion Criteria

Non-diabetic patients (HbA1c less than 6.5) Controlled diabetic patients (HbA1c 6.5-8)(ASA I and ASA II classification) Patients with age group till 60 years Patients with missing maxillary posterior teeth.
Sufficient bone height (distance between bone crest and maxillary sinus greater than or equal 8 mm).

Exclusion Criteria

ASA III,IV,V.
Patient with HbA1c level greater than 8 Patients with fluctuant HbA1c levels during the study period Patients under bone sparing treatment Patients with parafunctional habits Pregnant and lactating women smokers.

Primary Outcome Measures

Name	Time	Method
2.Molecular outcomes- Bone markers RANKL and OPG.	1.Radiographic outcomes- baseline(2 weeks) and 6 months. \| 2.Molecular outcomes- baseline(2 weeks),1month,3,months. \| 3.Microbiological count-baseline(2 weeks),1month.
1.Radiographic outcomes- peri-implant bone changes,Mean bone density.	1.Radiographic outcomes- baseline(2 weeks) and 6 months. \| 2.Molecular outcomes- baseline(2 weeks),1month,3,months. \| 3.Microbiological count-baseline(2 weeks),1month.
3.Microbiological count-Quantitative evaluation of porphyromonas gingivalis(Pg), tanerella forsythia(Tf), treponema denticola(Td).	1.Radiographic outcomes- baseline(2 weeks) and 6 months. \| 2.Molecular outcomes- baseline(2 weeks),1month,3,months. \| 3.Microbiological count-baseline(2 weeks),1month.

Secondary Outcome Measures

Name	Time	Method
1.Implant stability	2.Plaque index(FMPS) , Gingival index (FMGS)

Locations (1): Vishnu Dental College
🇮🇳
Godavari, ANDHRA PRADESH, India
Vishnu Dental College
🇮🇳Godavari, ANDHRA PRADESH, India
Dr Podili Alluri Vijay Kumar
Principal investigator
08919165668
vijaykumar.pa@vdc.edu.in