Heart Defects in Infants- Detection, Rescue and Care
Overview
- Phase
- Not Applicable
- Intervention
- Not specified
- Conditions
- Heart Defects, Congenital
- Sponsor
- Oslo University Hospital
- Enrollment
- 3000
- Locations
- 1
- Primary Endpoint
- Mortality
- Status
- Completed
- Last Updated
- 6 years ago
Overview
Brief Summary
The overall objective of this project is to optimize the use of diagnostic methods and follow-up programs in infants with congenital heart defects (CHDs) in order to reduce death and complications
Detailed Description
The project is designed as retrospective cohort study based on nationwide registry data of children born 2004-16. The project group has extensive experience of similar research, and includes representatives from different fields and levels of health care. The results will provide a solid fundament for improvement of today's clinical practice, including development of knowledge-based routines in neonatal medicine and planning of health care services. Implementation is given particular attention, and will be managed in an interdisciplinary setting. The project will be of major relevance for the patients and their families as well as medical professionals at all levels of health care.
Investigators
Henrik Holmstrøm
Professor
Oslo University Hospital
Eligibility Criteria
Inclusion Criteria
- •Fetuses with severe CHDs who were identified by antenatal ultrasound screening, and where the pregnancy was terminated
- •Children with severe congenital heart defects born in Norway 2004-18
Exclusion Criteria
- •Lack of parental consent
Outcomes
Primary Outcomes
Mortality
Time Frame: 0-2 years
All deaths including prenatal termination of pregnancy