The Effect of a Red Rice and Olive Extract Nutrition Supplement on Cholesterol Levels in Patients With Metabolic Syndrome
Phase 4
Completed
- Conditions
- Hypercholesterolaemia
- Registration Number
- NCT02065180
- Lead Sponsor
- Universiteit Antwerpen
- Brief Summary
This randomised controlled trial studies the effect of a commercially available nutritional supplement on cholesterol levels in people with metabolic syndrome and elevated cholesterol levels.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- All
- Target Recruitment
- 50
Inclusion Criteria
-
metabolic syndrome according to ATPIII criteria 3 of the following:
- waist circumference >88cm (in females) or >102cm (in males)
- triglycerides >150mg/dl
- HDL <40 (50)mg/dl in males (females)
- blood pressure>130/85 or treatment for AHT
- glucose >110mg/dl
Exclusion Criteria
- pregnancy
- treatment with cholesterol lowering drugs
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- PARALLEL
- Primary Outcome Measures
Name Time Method LDL level 2 months total cholesterol level 2 months triglyceride level 2 months HDL level 2 months
- Secondary Outcome Measures
Name Time Method BMI 2 months 8-OH-deoxyguanosine (8-OHdG) 2 months OxLDL 2 months malondialdehyde (MDA) 2 months side effects 2 months waist circumference 2 months
Related Research Topics
Explore scientific publications, clinical data analysis, treatment approaches, and expert-compiled information related to the mechanisms and outcomes of this trial. Click any topic for comprehensive research insights.
What molecular mechanisms underlie red rice and olive extract's cholesterol-lowering effects in metabolic syndrome?
How does the red rice and olive extract supplement compare to statins in managing hypercholesterolemia and metabolic syndrome?
Which biomarkers correlate with response to red rice and olive extract supplementation in patients with metabolic syndrome?
What are the potential adverse events associated with red rice and olive extract supplementation in hypercholesterolemia patients?
Are there synergistic effects when combining red rice and olive extract with other lipid-lowering agents like ezetimibe or PCSK9 inhibitors in metabolic syndrome?
Trial Locations
- Locations (1)
University of Antwerp
🇧🇪Antwerp, Belgie, Belgium
University of Antwerp🇧🇪Antwerp, Belgie, Belgium