ISRCTN04023349已完成未知
Effects of anti-mycobacterium treatment on temporal lobe necrosis following radiotherapy for nasopharyngeal carcinoma: a prospective, controlled study
Sun Yat-sen University (China)0 个研究点目标入组 60 人开始时间: 2013年4月18日最近更新:
适应症
试验速览
- 阶段
- 未知
- 状态
- 已完成
- 发起方
- 入组人数
- 60
研究概览
简要总结
- 2014 results in http://dx.doi.org/10.11648/j.jctr.20140205.12 (added 22/01/2019)
研究设计
- 研究类型
- Interventional
入排标准
- 性别
- All
入选标准
- •Patients who fulfilled the following eligibility criteria were recruited in this study:
- •1. Aged 18 to 65 years
- •2. Histopathologically proven cases of NPC who had undergone radiation therapy, with
- •negative brain MR before RT
- •3. Patients must have received cranial irradiation = 6 months prior to study entry
- •4. MRI evidence of bilateral temporal lobe edema and/or necrosis with
- •or without foci of contrast enhancement on MRI
- •5. Evidence of progressive neurologic signs or symptoms related with TLN
排除标准
- •Patients were excluded if they had:
- •1. Significant hepatic or renal insufficiency
- •2. Evidence of brain metastasis, brain abscess, any intracranial tumor, cerebral infarction,
- •demyelinating disease
- •3. Clinical manifestations such as fever, meningeal irritatation signs indicating meningitis
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