An Evaluation of Comfort and Tolerance of Surface Neuro Muscular Electrical Stimulation (NMES), When Applied to Parkinson's Disease Patients for Both Sensory and Motor Activation.
试验速览
- 阶段
- 不适用
- 入组人数
- 10
- 试验地点
- 1
- 主要终点
- Patient comfort in response to neuromuscular electrical stimulation in Parkinson's disease.
研究概览
简要总结
The purpose of this study is to investigate issues relating to comfort and tolerance to surface neuro muscular electrical stimulation in a parkinson disease population.
详细描述
The comfort and tolerance of Parkinson Disease (PD) patients to surface neuro muscular electrical stimulation (NMES) will be investigated.
Six muscle sites will be tested sensory, motor and pain thresholds recorded. Furthermore pain tolerance will be recorded as the level at which the stimulus is unbearable.
研究设计
- 研究类型
- Interventional
- 分配方式
- Na
- 干预模型
- Single Group
- 主要目的
- Supportive Care
- 盲法
- Single (Participant)
入排标准
- 年龄范围
- 40 Years 至 85 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •A diagnosis of idiopathic PD (UK, PD Brain Bank Criteria)
- •A Hoehn and Yahr stage of 2 - 4
- •Exhibiting Freezing of Gait or another gait abnormalityin the ON or OFF state.
- •An ability to mobilise independently for the purpose of research when in the 'off' state
- •An ability to walk unaided for 10 meters.
排除标准
- •A serious cognitive impairment (MMSE<24)
- •Pregnant or currently involved in another clinical trial.
- •Uncontrolled heart problems
- •Pacemakers
- •On opioid or neuropathic pain medication
结局指标
主要结局
Patient comfort in response to neuromuscular electrical stimulation in Parkinson's disease.
时间窗: 1 day
Participants will be tested over a range of stimulation intensities at different muscle sites. Primary outcome measure will be patient comfort and tolerance to neuromuscular electrical stimulation.
次要结局
未报告次要终点
研究者
Gearoid O Laighin
Professor
National University of Ireland, Galway, Ireland