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Clinical Trials/IRCT20220115053723N1
IRCT20220115053723N1
Completed
Phase 2

comparison study of the effects of duloxetine and venlafaxine on neuropathy in breast cancer patients with taxol-induced acute peripheral neuropathy

Tehran University of Medical Sciences0 sites80 target enrollmentTBD

Overview

Phase
Phase 2
Intervention
Not specified
Conditions
Not specified
Sponsor
Tehran University of Medical Sciences
Enrollment
80
Status
Completed
Last Updated
3 years ago

Overview

Brief Summary

No summary available.

Registry
who.int
Start Date
TBD
End Date
TBD
Last Updated
3 years ago
Study Type
Interventional
Sex
Female

Investigators

Eligibility Criteria

Inclusion Criteria

  • patients with breast cancer who treated with taxol (paclitaxel) for chemotherapy with peripheral neuropathic and neuropathic pain with confirmation of physical examination
  • pain score 3 or more according to MacGill questionnaire
  • No metastasis
  • life expectancy more than 3 months
  • Hospital anxiety and depression scale score less than 20 according to HADS questionnaire
  • Neuropathic score more than 3 in DN4 questionnaire.

Exclusion Criteria

  • metastatic breast cancer
  • pregnancy and breast feeding
  • HADS score more than 20
  • using antidepressant and anti epileptic drugs and opioids
  • paralytic neuropathic syndromes

Outcomes

Primary Outcomes

Not specified

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