Long term outcome of patients with symptomatic rheumatic atrial fibrillation
试验速览
- 阶段
- 不适用
- 状态
- 尚未招募
- 发起方
- 入组人数
- 500
- 试验地点
- 2
- 主要终点
- To study improvement in exercise capacity as measured by 6-minute walk test distance (6MWT) following systematic management of symptomatic RHDAF patients.
研究概览
简要总结
Rheumatic heart disease (RHD) continues to be an important cause of (42%) of atrial fibrillation (AF) in India (1). Atrial fibrillation in RHD affects younger patients ( 51.24 ± 15.36 years) compared to Non-valvular AF reported from the western population (2). This will have a significant socio economic implication because of the disability�’adjusted life years (DALYs).
The first Indian registry, the Indian Heart Rhythm Society (IHRS) atrial fibrillation (AF) studied 1000 patients with AF at twenty different cities across the country. It showed rheumatic heart disease (RHD) as the leading cause of (42%) of AF in India (1). In an Indian study, age of AF patients were 51.24 ± 15.36 years which is much younger than the western population (2). This emphasizes the huge economic implication because of the disability�’adjusted life years (DALYs) and need to adequately address the treatment of AF effectively.
研究设计
- 研究类型
- Observational
入排标准
- 年龄范围
- 18.00 Year(s) 至 95.00 Year(s)（—）
- 性别
- All
入选标准
- •CRHD patients with Atrial Fibrillation.
排除标准
- •Non-Rheumatic patients.
结局指标
主要结局
To study improvement in exercise capacity as measured by 6-minute walk test distance (6MWT) following systematic management of symptomatic RHDAF patients.
时间窗: minimum one-year follow-up
次要结局
- 1. To Study change in functional class over 1year follow-up.(2. To study improvement in cardiac biomarker NT-proBNP over 1year follow-up.)
研究者
Daljeet kaur saggu
AIG Hospitals