Synovectomy in Primary Total Knee Arthrplasty

Not Applicable

• Conditions: Arthroplasty, Replacement, Knee; Synovectomy
• Interventions: Other: Synovectomy

• Registration Number: NCT03778463
• Lead Sponsor: Ain Shams University

Brief Summary

The aim of total knee arthroplasty is to achieve best patient functional outcomes, improve patient pain score and satisfaction. Synovial proliferation is a common finding in arthritic knees. Surgeons can't decide if synovectomy is a crucial step in the operation. Studies didn't prove the clear benefits of synovectomy. We are aiming to perform a randomized clinical trial trying to reach the best evidence in that matter.

Detailed Description

Not available

Basic Information
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Recruitment & Eligibility
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Study & Design
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Trial Locations

Study Timeline

• Status Verified: 2018-12
• Study Start: 2018-12
• Study First Submitted: 2018-12-14
• Study First Submitted QC: 2018-12-14
• Last Update Submitted: 2018-12-14
• Study First Posted: 2018-12-19
• Last Update Posted: 2018-12-19
• Primary Completion: 2019-12
• Study Completion: 2020-12

Recruitment & Eligibility

• Status: UNKNOWN
• Sex: All
• Target Recruitment: 70

Inclusion Criteria

• patients with primary osteoarthritis undergoing primary total knee arthroplasty

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Exclusion Criteria

• Inflammatory arthritis
• Revision knee arthroplasty

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Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
Synovectomy	Synovectomy	-

Primary Outcome Measures

Name	Time	Method
Health related quality of life e.g. short form (SF12) scale	one year
Reoperation rate	one year
Range of motion	One year
knee pain e.g. visual analogue score (VAS) score	immediate postoperative
Functional outcome scores. e.g. knee society score (KSS)	one year
Revision rate	one year

Secondary Outcome Measures

Name	Time	Method
Postoperative hemoglobin level	immediate postoperative	gram/dl
Postoperative blood loss	immediate postoperative
Number of patients requiring transfusion	immediate postoperative
Infection rate	in first three month
Wound complications	in first 3 months

Trial Locations

Locations (1)

Ain Shams Univrsity; 🇪🇬 Cairo, Egypt