Intraretinal Cystoid Changes After Vitrectomy With Membrane Peeling
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 40
- 试验地点
- 1
- 主要终点
- Intraretinal cystoid changes
研究概览
简要总结
Aim of the study is to assess the rate of postoperative intraretinal cystoid changes after pars plana vitrectomy with membrane peeling and peribulbar application of triamcinolone acetonide and to examine possible risk factors for postoperative intraretinal cystoid changes.
详细描述
Epiretinal membranes (ERM) are disorders leading to vision loss and metamorphopsia. Vitrectomy with membrane peeling has developed to be the gold-standard in treatment of ERM. Nevertheless, there are about 10% of patients having intraretinal cystoid changes after surgery with potential for disturbance of visual acuity. The aim of the study is to assess the rate of postoperative intraretinal cystoid changes after pars plana vitrectomy with membrane peeling and peribulbar application of triamcinolone acetonide and to examine possible risk factors for postoperative intraretinal cystoid changes.
研究设计
- 研究类型
- Observational
- 观察模型
- Case Control
- 时间视角
- Retrospective
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •presence of an ERM
- •indication for membrane peeling defined as significant loss of vision and/or metamorphopsia due to the ERM
- •application of periocular triamcinolone acetonide at the end of surgery
- •at least one follow-up examination present in the patient's history
排除标准
- •macular edema caused by conditions other than ERM (such as choroidal neovascularization, diabetic macular edema, etc.)
结局指标
主要结局
Intraretinal cystoid changes
时间窗: 3 months
presence of intraretinal cystoid changes in OCT is assessed during the time period of 3 months after surgery
次要结局
- intraocular pressure (IOP)(3 months)
- distance corrected visual acuity(3 months)
研究者
Prim. Prof. Dr. Oliver Findl, MBA
Prof. Dr. Oliver Findl, MBA
Vienna Institute for Research in Ocular Surgery