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Clinical Trials/NCT04823754
NCT04823754
Completed
Not Applicable

Perception of the Doctor/Patient Relationship, Disease and Treatment Among Physicians and Their Patients Treated With Systemic Therapy for Hepatocellular Carcinoma

Assistance Publique - Hôpitaux de Paris2 sites in 1 country150 target enrollmentJuly 12, 2021

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
Hepatocellular Carcinoma
Sponsor
Assistance Publique - Hôpitaux de Paris
Enrollment
150
Locations
2
Primary Endpoint
Evaluate the concordance between the patient's perception of his prognosis and treatment side effects with the one of his treating physician.
Status
Completed
Last Updated
2 years ago

Overview

Brief Summary

atients with cancer face difficult choices that require balancing competing priorities such as survival, functional capacity and symptom relief. Most patients with advanced cancer (>80%) expect their sensitive discussions with physicians about prognosis and treatment choices, in order to be involved in the decision making process. Nevertheless, this kind of discussion is frequently lacking. Consequently, patients often have a biased view of their own prognosis such as an underestimation of disease severity, or unrealistic expectations for cure.

Patients with advanced hepatocellular carcinoma (HCC) may be treated with systemic therapies which may prolong survival, but are not curative. Patients with advanced HCC often report expectations for survival and treatment-related side-effects that differ from their treating physician. Accordingly, communication on prognostic and treatment choices is essential to obtain an accurate understanding of the disease that allows patients to make informed decisions. To the best of our knowledge, a thorough evaluation of the physician-patient communication quality has never been performed in advanced HCC patients.

The aim of our study, is to assess the perception of the expected prognosis, the treatment side-effects; by the patient and by his investigator during the first consultation before the initiation

Detailed Description

atients with cancer face difficult choices that require balancing competing priorities such as survival, functional capacity and symptom relief. Most patients with advanced cancer (\>80%) expect their sensitive discussions with physicians about prognosis and treatment choices, in order to be involved in the decision making process. Nevertheless, this kind of discussion is frequently lacking. Consequently, patients often have a biased view of their own prognosis such as an underestimation of disease severity, or unrealistic expectations for cure. Patients with advanced hepatocellular carcinoma (HCC) may be treated with systemic therapies which may prolong survival, but are not curative. Patients with advanced HCC often report expectations for survival and treatment-related side-effects that differ from their treating physician. Accordingly, communication on prognostic and treatment choices is essential to obtain an accurate understanding of the disease that allows patients to make informed decisions. To the best of our knowledge, a thorough evaluation of the physician-patient communication quality has never been performed in advanced HCC patients. The aim of our study, is to assess the perception of the expected prognosis, the treatment side-effects; by the patient and by his investigator during the first consultation before the initiation

Registry
clinicaltrials.gov
Start Date
July 12, 2021
End Date
November 4, 2022
Last Updated
2 years ago
Study Type
Observational
Sex
All

Investigators

Responsible Party
Sponsor

Eligibility Criteria

Inclusion Criteria

  • Patient over 18 years of age
  • Patient informed and not objecting to participate in the study
  • Patient with advanced hepatocellular carcinoma.
  • Patient treated with systemic therapy

Exclusion Criteria

  • Locoregional treatment combined with systemic treatment
  • Pregnancy in progress
  • Candidate for surgery or locoregional therapy
  • Patient with state medical aid (AME)

Outcomes

Primary Outcomes

Evaluate the concordance between the patient's perception of his prognosis and treatment side effects with the one of his treating physician.

Time Frame: 12months

Use of survey completed by the patient and the doctors to assess the primary endpoint

Secondary Outcomes

  • Evaluation of patient satisfaction with the information received during the consultation(12 months)
  • Compare the patient's expectations for the aforementioned items to those of his physician and the degree of concordance between them.(12 months)
  • Assessment of patient-reported symptoms of anxiety and depression(12 months)
  • Evaluate the association between individual prognosis expectation (patient and physician) and data from the available literature.(12 months)

Study Sites (2)

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