Comparison of Different Mucoactive Agents for the Care of the Intubated Patient in a Surgical Trauma Intensive Care Unit

Not Applicable

Completed

• Conditions: Mucus Obstruction; Intubation

• Registration Number: NCT00131521
• Lead Sponsor: The University of Texas Health Science Center at San Antonio

Brief Summary

This study compares N-acetylcysteine (mucomyst) and sodium chloride to determine their efficacy in the prevention of pulmonary mucus obstruction and retention in intubated patients admitted to the surgical trauma intensive care unit (STICU).

Detailed Description

Not available

Study Timeline

• Study Start: 2005-01
• Study First Submitted: 2005-08-17
• Study First Submitted QC: 2005-08-17
• Study First Posted: 2005-08-18
• Study Completion: 2007-12
• Status Verified: 2009-06
• Last Update Submitted: 2009-06-20
• Last Update Posted: 2009-06-23

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 260

Inclusion Criteria

• Intubated and admitted to the Surgical Trauma Intensive Care Unit (STICU)
• Subjects must be eligible to start treatment within 24 hours of their initial intubation

Read More

Exclusion Criteria

• Patient anticipated to be extubated within 24 hours following STICU admission
• Hypersensitivity to acetylcysteine.
• Pregnancy

Read More

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: SINGLE_GROUP

Primary Outcome Measures

Name	Time	Method
prevention of pulmonary mucus obstruction

Secondary Outcome Measures

Name	Time	Method
days of mechanical ventilation

Trial Locations

Locations (1)

Univesity Hospital; 🇺🇸 San Antonio, Texas, United States