Randomized Controlled Clinical Study to evaluate the efficacy of Pathyadi Churna in the management of chhardi in children
试验速览
- 阶段
- 2/3 期
- 状态
- 尚未招募
- 发起方
- 入组人数
- 93
- 试验地点
- 1
- 主要终点
- Prasek (Excessive salivation )
研究概览
简要总结
The kaumarbhritya is a branch of ayurveda which deals with study of childhood disease and their management.
Chhardi is one of the common diseases of early growing age which resembles vomiting as per modern science.Chhardi (vomiting) or Emessis is the abnormal emptying of stomach and upper part of intestine through oesophagus and mouth.
According to Ayurved chhardi is a disease of Annavaha strotas.
In Ayurveda there are five types of chhardi i.e. Vataj, Pittaj, Kaphaj, Sannipataj and Dvishtharthyogaj / Agantuja. Vitiated udan vayu along with vyan vayu brings the contents of stomach upward and expels through mouth. This condition is associated with vitiated Pitta and Kapha doshas.
The drug to be used in child for suppression of vomiting within short duration as this may lead to severe complications in children. Some of which may be catastrophic and life threatening. Therefore determining the cause and treatment of child vomiting has major importance.
RATIONALE OF STUDY
Chhardi is the commonest disease in children hence the need to be controlled by ayurvedic medicine without any side effects. To break the pathology chhardi by agnideepana.
The conventional treatment in modern medicine has side effects. Prochlorperazine should not be used in children due to high risk of extra pyramidal reaction, while antihistamine should be avoided due to sedation. Metoclopramide has side effects like sedation ,dizziness ,diarrhoea, muscle dystonia (Specially in children.Long term use can cause parkinsonism ,galactorrhoea , and gynacomastia. Ondensetron has side effects like - headache, mild constipation, or diarrhoea and
abdominal discomfort.
NULL HYPOTHESIS (H0)
Pathyadi churna is not effective in the management of chhardi in children.
ALTERNATIVE HYPOTHESIS (H1)
Pathyadi churna is effective in the management of chhardi in children
研究设计
- 研究类型
- Interventional
- 分配方式
- Coin toss, Lottery, toss of dice, shuffling cards etc
- 盲法
- Participant Blinded
入排标准
- 年龄范围
- 6.00 Year(s) 至 16.00 Year(s)（—）
- 性别
- All
入选标准
- •Age group between 6 to 16 years.
- •Patients irrespective of their gender, religion and socio economic class.
- •Patients having sign and symptoms of chhardi as mentioned in Ayurvedic text.
排除标准
- •Patient suffering from chhardi as upadrava of other disease patient suffering from Atisar as well as Chhardi Patients of known anatomical defects and metabolic disorders.
- •Patients with some and severe dehydration with chronic disorders like Cirrhosis of liver.
- •Patients with any other systemic disorders, neurological conditions like e.g. meningitis, malignancies , cerebral tumor All surgical cases.
- •Sannipataj and Dvishtharthyogaj.
结局指标
主要结局
Prasek (Excessive salivation )
时间窗: Baseline, 3rd day
Aruchi (Anorexia)
时间窗: Baseline, 3rd day
Hrullas (Nausea)
时间窗: Baseline, 3rd day
次要结局
- Chhardi vega(Dehydration)
研究者
VD. Rohit Ranchhod Patil
C.S.M.S.S. Ayurved Mahavidyalaya and Rugnalaya Kanchanwadi Aurangabad