The Effect of Using Desensitizers Containing S-PRG Versus Sodium Fluoride With Functionalized Tri-Calcium Phosphate In Treatment Of Dentin Hypersensitivity In Adult Patients Over 6 Months: A Randomized Clinical Trial
试验速览
- 阶段
- 不适用
- 状态
- 尚未招募
- 发起方
- 入组人数
- 50
- 试验地点
- 2
- 主要终点
- Dentin hypersensitivity reduction
研究概览
简要总结
The goal of this clinical trial is to compare the effect of desensitizer containing S-PRG have similar effect as sodium fluoride with functionalized tri-calcium phosphate containing desensitizer in relieving dentinal hypersensitivity in adult patients for six months follow-up. patients will be asked to report pain degree on the visual analogue scale (VAS) along the follow up periods on both groups.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- Double (Participant, Outcomes Assessor)
盲法说明
Participants and both assessors will be blind to the type of material used.
入排标准
- 年龄范围
- 18 Years 至 50 Years（Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •Good oral hygiene.
- •Cooperative patients who show interest to participate in the study and welling to sign the informed consent.
- •Healthy patients with no history of previous systematic diseases that can affect their oral health.
- •Normal and healthy gingival tissue.
- •Teeth that have no cavitation or restorations.
- •Patients with at least 20 natural permanent teeth and at least two teeth with a VAS score from 4 to
- •Anterior teeth.
排除标准
- •Allergic to the ingredients used in the study.
- •Gastrointestinal disorders (They have repeated vomiting attacks).
- •Medically compromised (They cannot tolerate the procedures).
- •Taking desensitizing treatment in the last 6 months (It affects the outcome).
- •Taking anti-inflammatory drugs (It affects the hypersensitivity perception).
- •Pregnant females (They complain from nausea and repeated vomiting attacks)
- •Smokers (Smoking will affect the oral hygiene and periodontal health).
研究组 & 干预措施
Varnish contains S-PRG (PRG Barrier Coat from Shofu)
Treatment of dentin hypersensitivity by application of tooth varnish containing S-PRG.
干预措施: Tooth varnish (PRG Barrier Coat from Shofu) (Procedure)
Varnish contains sodium fluoride and functionalized tri-calcium phosphate(Clinpro white varnish 3M)
Treatment of dentin hypersensitivity by application of tooth varnish containing sodium fluoride with functionalized tri-calcium phosphate.
干预措施: Tooth varnish (Clinpro white varnish 3M) (Procedure)
结局指标
主要结局
Dentin hypersensitivity reduction
时间窗: assessment will be done immediately after the treatment then after 1 week, 4 weeks, 3 months and 6 months.
The participants will point out the degree of sensitivity on the VAS scale (0-10) chart.
次要结局
未报告次要终点
研究者
Eman Omar Elfarouk
masters degree student
Cairo University