Skip to main content
MedPath Trial logoMedPath TrialMedPath Trial Home
Clinical Trials/TCTR20200512002
TCTR20200512002Recruiting未知

Effect of Intravenous Acetaminophen on Postoperative Morphine Consumption in Benign Open Abdominal Gynecological Surgeries: A double-blind, randomized, placebo-controlled trial

Faculty of Medicine, Chiang Mai University0 sites100 target enrollmentStarted: May 12, 2020Last updated:
Share to TwitterShare to FacebookShare to LinkedInShare to Reddit
Conditions

Trial Snapshot

Phase
未知
Status
Recruiting
Sponsor
Enrollment
100
Study OverviewEligibility CriteriaInvestigatorsRecords & IdentifiersSimilar Trials

Study Overview

Brief Summary

No summary available.

Study Design

Study Type
Interventional

Eligibility Criteria

Ages
18 Years to 65 Years (—)
Sex
Female

Inclusion Criteria

  • •1.Women aged 18-65 years old
  • •2.Patients who undergoing elective benign open abdominal gynecological surgery
  • •3.American Society of Anesthesiologists (ASA) Class I-III

Exclusion Criteria

  • •1.Patients with known allergy to acetaminophen, parecoxib, sulfonamides, aspirin or opioids
  • •2.Patients with either acute or chronic liver disease (defined as abnormal rising AST ALT, hypoalbuminemia, prolonged INR, or evidence from imaging diagnosis)
  • •3.Patients with moderate to severe pain before surgery
  • •4.Third trimester pregnant patients or lactation period
  • •5.Patients receive any additional neuraxial block or peripheral nerve blocks for pain control
  • •6.Patients with history of opioid abuse or chronic opioid use for greater than 3 months
  • •7.Patients with suspected malignant gynecological disease intraoperatively and undergo extended lymph node dissection or complete surgical staging
  • •8.Patients with contraindication to parecoxib (post CABG surgery, established ischemic heart disease, peripheral arterial disease and/or cerebrovascular disease, inflammatory bowel disease, Child-Pugh score ≥ 10, active peptic ulcer/ GI bleeding, known hypersensitivity to sulfonamides)

Investigators

Sponsor
Faculty of Medicine, Chiang Mai University

Similar Trials

Recruiting
Phase 3
Effect of iv Acetaminophen on pain in hip fractureHip fracture.Fracture of femur
IRCT20180225038861N1Sabzevar University of Medical Sciences66
Not yet recruiting
Not Applicable
The effect of intravenous acetaminophen on postoperative temperature after cardiac surgery with cardiopulmonary bypassPatients after cardiac surgery
JPRN-UMIN000033064agasaki University Hospital48
Completed
Phase 3
The effect of intravenous acetaminophen on postoperative pain control after esophageal cancer surgery, a prospective randomized study.Esophageal cancer
JPRN-UMIN000026257Tokushima university60
Completed
Not Applicable
Effect of Acetaminophen in preventing postoperative shivering: A randomized, triple-blind, placebo-controlled studyPatients who will have elective gynecologic surgery
JPRN-UMIN000020043niversity of the Ryukyus96
Recruiting
Phase 3
The Efficacy of Perioperative Intravenous Acetaminophen for Off-pump CABGangina pectoris, old/subacute myocardial infarction, post operative pain
JPRN-UMIN000015653IMS Katsushika Heart Center150