General Anesthesia Versus Loco-Regional Anesthesia for Transcarotid Trancatheter Aortic Valve Replacement

Not yet recruiting

• Conditions: Aortic Stenosis

• Registration Number: NCT06870734
• Lead Sponsor: University Hospital, Caen

Brief Summary

Transcarotid transcatheter aortic valve replacement (Transcarotid TAVR) has been increasingly used as an alternative to the transfemoral approach. The general anesthesia, locoragional anesthesia or local anesthesia are three anesthesia techniques that can be used for transcarotid TAVR. We aim to compare the locoregional approach to gerneral anesthesia.

Detailed Description

Not available

Study Timeline

• Status Verified: 2025-03
• Study First Submitted: 2025-03-06
• Study First Submitted QC: 2025-03-06
• Last Update Submitted: 2025-03-06
• Study Start: 2025-03-07
• Study First Posted: 2025-03-11
• Last Update Posted: 2025-03-11
• Primary Completion: 2025-12-31
• Study Completion: 2026-03-06

Recruitment & Eligibility

• Status: NOT_YET_RECRUITING
• Sex: All
• Target Recruitment: 44

Inclusion Criteria

• Adult patients who underwent a transcarotid TAVR at the University Hospital of Caen between October 2021 (when the first TAVR was performed under locoregional anesthesia) and December 2024

Exclusion Criteria

• Patient's refusal to allow data collection and lack of data regarding the primary endpoint

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Primary endpoint	7 days	Composite endpoint combining mortality and stroke in the first post-operative week

Secondary Outcome Measures

Name	Time	Method
Vasopressive drugs	1 day	Use of vasopressive drugs during the intervention
Death	7 days	Death occuring during the first week after intervention
Stroke	7 days	Stroke occuring during the first week after the intervention
30 day mortality	30 days	Death occuring during the first month after intervention
1 year mortality	1 year	Death occuring during the first year after intervention