Correlation of subarachnoid space depth obtained from formula versus actual measurement at lumbar region to derive appropriate formula in patients undergoing spinal anaesthesia at a tertiary care centre- An observational study
Trial Snapshot
- Phase
- Not Applicable
- Status
- Not yet recruiting
- Sponsor
- Enrollment
- 300
- Locations
- 1
- Primary Endpoint
- 1. correlation between subarachanoid space depth estimation by derived formula and the actual measurement at lumbar region in patients (males, females and pregnant women) undergoing spinal anesthesia."
Study Overview
Brief Summary
Subarachnoid block is a commonly practiced anaesthesia technique for lower abdominal and limb surgeries, including cesarean sections.Performed using an anatomical landmark guided, blind approach, its sucess depends on factors like height weight BMI and BSA.In conditions such as obesity, pregnancy or edema estimating subaracnoid space depth is crucial to minimize failed attempts and complications. Existing predictive formulas, largely derived from western population, require validation in indians hence this study aims to establish a reliable, population-specific model for accurate SSD estimation.
A prospective observational study will be conducted at hospitals attached to BMCRI form febrauary 2026 to april 2026 to determine skin to subarachnoid space depth in indian adults undergoing spinal anaesthesia and to assess the accuracy of anthropometric data (height, weight,BMI,BSA) will be collected and actual SSD will be measured during midline lumbar puncture. Predicted SSDs will be calculated using existing and newly derived equations to validate populaton- specific accuracy and improve procedural precision and safety.
Study Design
- Study Type
- Interventional
- Allocation
- Na
- Masking
- None
Eligibility Criteria
- Ages
- 18.00 Year(s) to 60.00 Year(s) (—)
- Sex
- All
Inclusion Criteria
- •ASA grade I/II patients posted for various elective surgeries under spinal anaesthesia in general, gynecology and obstetrics surgery unit.
Exclusion Criteria
- •1.Patients with known hypersensitivity/contraindication to study drugs.
- •2.Patients with coagulation disorders, infection at the site of spinal injection.
- •3.Patients with severe renal/hepatic/respiratory or cardiac disease.
- •4.Pregnant patients with hypertensive disorders/in patients where paramedian approach of spinal anaesthesia will be used.
- •5.Patients with neurological/psychiatric/neuromuscular disorders/spine anomaly.
- •6.associated medical illness with relative contraindication to spinal anaesthesia.
Outcomes
Primary Outcomes
1. correlation between subarachanoid space depth estimation by derived formula and the actual measurement at lumbar region in patients (males, females and pregnant women) undergoing spinal anesthesia."
Time Frame: at baseline and immediate after giving spinal anaesthesia
2.validation of the formulas derived from the previous study by using sensitivity analysis in patients (males, females and pregnant women) undergoing spinal anesthesia.
Time Frame: at baseline and immediate after giving spinal anaesthesia
Secondary Outcomes
- Derivation of appropriate formula for subarachanoid space depth calculation based on height, weight, BMI and BSA from the data obtained from this study.(within 1 minute of giving spinal anesthesia n)
Investigators
DR YATHISH S K
Bangalore medical college and research institute