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临床试验/NCT06038305
NCT06038305招募中不适用

Prevalence of Anemia and Growth Assessment of Children Admitted With Acute Gastroenteritis in Assiut University Children Hospital

Assiut University1 个研究点 分布在 1 个国家目标入组 297 人开始时间: 2024年1月1日最近更新:
适应症

试验速览

阶段
不适用
状态
招募中
入组人数
297
试验地点
1
主要终点
Determine association between anemia and acute gastroenteritis in infants and children.

研究概览

简要总结

  1. Assessment of the growth parameters in infants admitted with acute gastroenteritis.
  2. Determine the prevalence of anemia in infants admitted with acute gastroenteritis.

详细描述

Gastroenteritis is inflammation of the stomach, small intestine, or large intestine, leading to a combination of abdominal pain, cramping, nausea, vomiting, and diarrhea. Acute gastroenteritis usually lasts fewer than 14 days. Worldwide, gastroenteritis affects 3 to 5 billion children each year. Up to 40% of children aged less than 5 years with diarrhea are hospitalized with rotavirus. Also, some microorganisms have been found predominantly in resource-constrained nations, including Shigella spp, Vibrio cholerae, and the protozoan infections. Malnutrition, immunosuppression, young age, and an increase in the preceding diarrhea burdens are risk factors for the development of persistent diarrhea. A substantial proportion of global malnutrition is due to impaired intestinal absorptive function resulting from multiple and repeated enteric infections. These include recurrent acute infections as well as persistent infections, even those without overt liquid diarrhea.

Child growth is internationally recognized as the best global indicator of physical well-being in children because poor feeding practices-both in quantity and quality-and infections, or more often a combination of the two, are major factors that affect physical growth and mental development in children. The most important measurements needed for growth assessment are recumbent length or height, weight and head circumference. These fundamental anthropometric measures should be obtained and interpreted at each well child visit, and are typically sufficient for growth assessment.

In this study, the prevalence of anemia and growth of infants admitted with acute gastroenteritis at Assiut University Children Hospital will be assessed. Anemia is a global public health problem, with important consequences for human health and the social and economic development of each nation. It results from single or multiple causes that act simultaneously, influencing children's health, their cognitive and physical development, and immunity, increasing the risk of infections and infant mortality.

研究设计

研究类型
Observational
观察模型
Other
时间视角
Cross Sectional

入排标准

年龄范围
1 Month 至 2 Years(Child)
性别
All
接受健康志愿者

入选标准

  • Infants with acute gastroenteritis.
  • Infants aged from 1 month and up to 2 years.

排除标准

  • Infants aged less than 1 month and more than 2 years.
  • Infants with persistent and chronic diarrhea.
  • Infants with acute gastroenteritis in association with chronic disease

结局指标

主要结局

Determine association between anemia and acute gastroenteritis in infants and children.

时间窗: baseline

assess anemia in children with acute gastroenteritis and if anemia affect severity of acute gastroenteritis

次要结局

未报告次要终点

研究者

申办方类型
Other
责任方
Principal Investigator
主要研究者

Gehad Ali Sayed

Resident physician, Family Medicine department

Assiut University

研究点 (1)

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