se of Platelet Rich Fibrin sheet in repair of ear drum
Phase 3
- Conditions
- Health Condition 1: H661- Chronic tubotympanic suppurative otitis mediaHealth Condition 2: O- Medical and Surgical
- Registration Number
- CTRI/2024/04/065658
- Lead Sponsor
- Dept of ENT AIIMS Mangalagiri
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- ot Yet Recruiting
- Sex
- Not specified
- Target Recruitment
- 0
Inclusion Criteria
1. Patients of chronic otitis media with inactive mucosal type.
2.Patients with conductive hearing loss less than 40 db.
3.Age group between 18-60 Years.
4.Patients With inactive ear for atleast 6 weeks
Exclusion Criteria
1.Patients with sensorineural hearing loss.
2.Pregnancy.
3.Patients with bleeding diathesis.
4.Patients with ossicular chain abnormalities.
5.Patients with mastoiditis, cholesteatoma and granulation tissue in middle ear.
6. Patients who refuses consent for PRF.
7.Patients with comorbidities like uncontrolled diabetes, hypertension, nasal allergies and COPD.
8.Patients with previous middle ear surgery, nasopharyngeal or skull base pathologies.
9. Patients coming for revision surgery.
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method graft uptakeTimepoint: 6 weeks
- Secondary Outcome Measures
Name Time Method change in hearing thresholdTimepoint: 3 months