Effect of the NBS on the treatment of nosocomial infections
Phase 3
Recruiting
- Conditions
- Hospital-acquired bloodstream infections.Bacterial infection, unspecifiedA49.9
- Registration Number
- IRCT20230116057135N3
- Lead Sponsor
- Tehran University of Medical Sciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- All
- Target Recruitment
- 94
Inclusion Criteria
Confirmation of the occurrence of sepsis in patients with the initial assessment of the patient's clinical symptoms and laboratory parameters
Patients over 18 years old
Primary diagnosis of sepsis (have at least two of the following four symptoms: hypothermia or hyperthermia, tachycardia, tachypnea, and leukocytosis or leukopenia) by an infectious specialist or a positive MDR culture
Exclusion Criteria
History of consuming corticosteroids and immunosuppressive drugs
Pregnant and lactating mothers
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Measurement of inflammatory factors. Timepoint: Measurement at the beginning of the study (before the start of the intervention) and 14 days after the start of NBS powder consumption. Method of measurement: Gold standard methods (ESR measurement by Westergren method, CRP measurement by Electrochemical Immunoassay method).;Measurement of white blood cells. Timepoint: Measurement at the beginning of the study (before the start of the intervention) and 14 days after the start of NBS powder consumption. Method of measurement: Cell Counter.
- Secondary Outcome Measures
Name Time Method Mortality Rate. Timepoint: After completing the intervention. Method of measurement: Checking the patient's clinical symptoms.