Role of naturally occurring dietary salicylates in Irritable Bowel Syndrome
Not Applicable
Completed
- Conditions
- Irritable bowel syndromeOral and Gastrointestinal - Other diseases of the mouth, teeth, oesophagus, digestive system including liver and colon
- Registration Number
- ACTRN12620001250921
- Lead Sponsor
- Monash University
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- All
- Target Recruitment
- 10
Inclusion Criteria
Patients with irritable bowel syndrome based on Rome III criteria.
Exclusion Criteria
- coeliac disease
- pregnancy and breastfeeding,
- other significant co-morbid conditions such as diabetes and inflammatory bowel disease.
- previously received advice or information on a low chemical diet.
- taking pharmacological agents like laxatives to alter their symptoms.
- taking aspirin or any other drugs containing or delivering salicylates for at least two weeks prior to the commencement of the study.
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method The primary endpoint was the difference in overall gastrointestinal symptoms measured by the 100-mm Visual Analogue Scale on the low-salicylate diet compared to those on the high-salicylate diet. [All comparisons were made using average symptom scores of the last three days of the respective dietary periods.]
- Secondary Outcome Measures
Name Time Method