Efficacy at One Year of Combined Injections of Plasma Rich in Platelets and Hyaluronic Acid in Knee Osteoarthritis

Recruiting

• Conditions: Knee Osteoarthritis; Hyaluronic Acid; Platelet Rich Plasma

• Registration Number: NCT05039463
• Lead Sponsor: Centre Hospitalier Universitaire, Amiens

Brief Summary

The French Society of Rheumatology cannot rule on the value of intra-articular injections of PRP due to the lack of hindsight and insufficient data. In fact, the injection protocols are very heterogeneous in terms of preparation method, the presence or not of leukocytes, the number of centrifugations, the volume injected, the ultrasound guidance, which makes it difficult to analyze the literature. The investigator objective is therefore to evaluate the effectiveness of combined injections of PRP and hyaluronic acid.

Detailed Description

Not available

Study Timeline

• Study Start: 2021-08-31
• Study First Submitted: 2021-08-31
• Study First Submitted QC: 2021-09-02
• Study First Posted: 2021-09-09
• Status Verified: 2023-02
• Last Update Submitted: 2023-02-07
• Last Update Posted: 2023-02-08
• Primary Completion: 2023-09
• Study Completion: 2023-09

Recruitment & Eligibility

• Status: RECRUITING
• Sex: All
• Target Recruitment: 100

Inclusion Criteria

• age : > 18 years old
• Patients benefiting, in the context of knee osteoarthritis, from viscosupplementation alone or from two injections of PRP, in combination with HA, at the Amiens University Hospital.

Exclusion Criteria

• Patient refusal to use the data
• Language barrier
• Age less than 18 years old.

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
change of the visual analogue scale (VAS) from the "PRP + HA" group on the "HA alone" group	up to one year

Trial Locations

Locations (1)

CHU Amiens; 🇫🇷 Amiens, France