Impact of Smoking, BZD and Obesity on Severe Obstructive Sleep Apnea (sOSA)
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 920
- 主要终点
- Apnea Hypopnea Index
研究概览
简要总结
In this study the investigators will analyze the influence of smoking, benzodizepine use, and obesity among patients with severe Obstructive Sleep Apnea (sOSA).
详细描述
This study is a retrospective study. Patients enrolled: all patients with a PSG (polysomnography) between 1st January 2014 and 30th June 2015.
First analysis: influence of smoking, benzodiazepine use, and obesity on the AHI (Apnea Hypopnea Index: the number of apnea and hypopnea per hour of sleep).
Second analysis: only among patients with sOSA: influence of smoking, benzodiazepine use, and obesity on sleep fragmentation and night oximetry.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Retrospective
入排标准
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •All patients registered for an overnight PSG at Clinique Saint-Luc of Bouge
排除标准
- 未提供
结局指标
主要结局
Apnea Hypopnea Index
时间窗: 1 day
Apnea Hypopnea Index (AHI) is defined as the number of apnea and hypopnea per hour of sleep. It is the major determinant of the severity of OSA.
次要结局
- Sleep fragmentation defined by the percentage of time spent in each of the four stades of sleep (Stade 1, Stade 2, Slow wave sleep and Rapid Eye Movements)(1 day)
- Time spent under 90% of SpO2 during the night(1 day)
研究者
Eric DEFLANDRE, MD, FCCP
MD, FCCP
Astes