Role of Two Rehabilitative Treatments and Diet in the Modulation of Inflammation in Patients With Knee Prosthesis.
- Conditions
- Knee Pain Swelling
- Registration Number
- NCT04580069
- Lead Sponsor
- Presidio Ospedaliero di Asiago
- Brief Summary
The investigators studied the influence of two aproved rehabilitative treatments, connective tissue techniques and lymphatic drainage, on acute inflammation markers. Furthermore, the role of mediterranean diet on the same values was investigated in the first postoperative period
- Detailed Description
The main objective of this study is to demonstrate the effectiveness of lymphatic drainage and connective tissue techniques in modulating systemic inflammation. Another objective is to evaluate the existence, at baseline, of a correlation between the inflammation indices and the level of adherence to the Mediterranean diet.
Methods. 34 patients were recruited, and divided into three groups. The control group followed the normal rehabilitation protocol. The other two groups were subjected, in addition to the standard treatment, to manual lymphatic drainage treatment or connective tissue techniques. The outcomes (PCR, ESR, Oedema) were recorded in three stages: upon entering the hospital, 1 week after entry and at follow-up 21 days after surgery.
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- All
- Target Recruitment
- 34
Not provided
- Joint replacements from other Units
- Inflammatory arthropathies
- Autoimmune / rheumatic diseases
- Obesity
- Diabetes mellitus
- Infections
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- PARALLEL
- Primary Outcome Measures
Name Time Method ESR variation 21 days blood test
CRP variation 21 days blood test
lower limb oedema 21 days leg circumference
- Secondary Outcome Measures
Name Time Method
Trial Locations
- Locations (2)
presidio ospedaliero di Asiago
🇮🇹Asiago, Vicenza, Italy
ULSS 7 Pedemontana
🇮🇹Asiago, Vicenza, Italy
presidio ospedaliero di Asiago🇮🇹Asiago, Vicenza, Italy