Prospective study of critical events during anaesthesia for non-operating room procedures in oncology patients

Prospective Study of Critical Events During Anaesthesia for Non-Operating Room Procedures in Oncology Patients.

This study aims to evaluate the incidence, nature, and contributing factors of critical events during non-operating room procedures in cancer patients, with the goal of enhancing peri-procedural safety and aligning practice with the unique needs of this vulnerable population. It will be a  prospective observational study done over a period  of 6 months. We will recruit all elective and emergency patients posted on the same day for a diagnostic or a therapeutic procedure under General Anaesthesia /sedation at all the following non- operating room procedures (CT scan, MRI suite, radiation therapy, interventional radiology, proton beam therapy, endoscopy suite, bone marrow procedure room and minor OT room). The critical events in all the elective and emergency non-operative procedures requiring anaesthesia (general anaesthesia/ monitored anaesthesia care) will be recorded. We intend to capture timing of occurrence of the event, type of event (airway/ respiratory/ haemodynamic changes / allergy, incorrect drug use/ drug error) action taken and patient outcome. The critical events are pre-defined based on established literature. The case record forms will be filled for each patient done under anaesthesia (general anaesthesia/

monitored anaesthesia care) by the anaesthetists of the designated location. The case record forms will be received at the end of the day by the primary investigators, co-investigators and research nurse to record the events.  Data collection will be anonymised and data will be securely stored. Descriptive statistics will be used to summarize baseline characteristics, with continuous variables presented as mean +/- standard deviation (SD) and categorical variables as frequencies and percentages. Logistic regression analysis will be done to identify significant factors associated with post procedure complications.