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A Study of LY3209590 Compared to Degludec in Adults With Type 2 Diabetes Who Are Starting Basal Insulin for the First Time

Phase 3
Conditions
Diabetes,Type 2 Diabetes
Registration Number
JPRN-jRCT2031220290
Lead Sponsor
Masaki Takeshi
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
ot Recruiting
Sex
All
Target Recruitment
912
Inclusion Criteria

Have diagnosis of T2D according to the World Health Organization Criteria
-Have an HbA1c of 7.0% - 10% inclusive, at screening
-Are on a stable treatment of at least 1 antihyperglycemic medication, for at least 3 months prior to screening, and willing to continue the stable treatment for the duration of the study

Exclusion Criteria

-Have a diagnosis of T1D, latent autoimmune diabetes, or specific type of diabetes other than T2D, for example, monogenic diabetes, diseases of the exocrine pancreas, or drug induced or chemical-induced diabetes.
-Have a history of >1 episode of ketoacidosis or hyperosmolar state or coma requiring hospitalization within 6 months prior to screening.
-Have had severe hypoglycemia episodes within 6 months prior to screening.
-Have known hemoglobinopathy, hemolytic anemia or sickle cell anemia, or any other traits of hemoglobin abnormalities known to interfere with the measurement of HbA1c.
-Have had New York Heart Association Class IV heart failure or any of these cardiovascular conditions within 3 months prior to screening
-acute myocardial infarction
-cerebrovascular accident (stroke), or
-coronary bypass surgery.
-Have had gastric bypass (bariatric) surgery, restrictive bariatric surgery, for example Lap-Band, or sleeve gastrectomy within 1 year prior to screening
-Have had significant weight gain or loss within 3 months prior to screening, for example,>= 5%.

Study & Design

Study Type
Interventional
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
Secondary Outcome Measures
NameTimeMethod
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