ACTRN12619000629134已完成未知
The Central Neurobiological and Immunological Effects of Exercise in Individuals with Chronic Pain.
适应症
试验速览
- 阶段
- 未知
- 状态
- 已完成
- 入组人数
- 16
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomised controlled trial
- 主要目的
- Treatment
- 盲法
- Blinded (masking used)
入排标准
- 年龄范围
- 18 Years 至 55 Years（—）
- 性别
- All
入选标准
- •Inclusion criteria – WAD
- •- Chronic whiplash associated disorder (>12 weeks duration)
- •- Aged between 18 and 55 years
- •o The lower age limit of 18 years will be applied as the brain in children is still in development which could potentially affect the MR outcomes. An upper age limit of 55 years will be applied to limit the possible effect of degenerative changes in the aging brain.
- •- Moderate neck pain intensity (at least 4/10 on a 0-10 numeric rating scale)
- •- Pain moderately interferes with daily activities (assessed using one item* from the SF-36 questionnaire)
- •- Currently low level of physical activity (assessed with the Godin-Shephard activity questionnaire)
- •- Motivated to commit to an eight-week exercise program
- •- Able to lie in an MRI scanner on their back for one hour
- •- Free from metal implants or pacemaker
- •* During the past 4 weeks, how much did pain interfere with your normal work (including both work outside the home and housework)?
- •Inclusion criteria – healthy controls
- •- No current neck pain, nor having had treatment for neck/shoulder complaints in the past 5 years
- •- No history of injury or trauma to the neck or head
- •- No current musculoskeletal pain in any body area
- •- Aged between 18 and 55 years
- •o The lower age limit of 18 years will be applied as the brain in children is still in development which could potentially affect the MR outcomes. An upper age limit of 55 years will be applied to limit the possible effect of degenerative changes in the aging brain.
- •- Currently low level of physical activity (assessed with the Godin-Shephard activity questionnaire)
- •- Motivated to commit to an eight-week exercise program
- •- Able to lie in an MRI scanner on their back for one hour
- •- Free from metal implants or pacemaker
- •- Matched to an individuals with WAD based on sex and age
排除标准
- •Exclusion criteria – WAD and healthy individuals
- •- History of migraine headaches
- •- Surgery to the neck
- •- Diabetes
- •- Posttraumatic stress symptoms (assessed on the PCL-5)
- •o Individuals with substantial posttraumatic stress symptoms will be excluded from this study as psychological stress may interfere with adherence to the exercise program,58 the neurobiological effects of exercise, and the effects of exercise on health outcomes.
- •- Currently receiving treatment for their neck pain (e.g., physiotherapy, chiropractic, or similar)
- •- Comorbidities preventing regular exercise
- •- Pregnant or breastfeeding
- •- Claustrophobic
研究者
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