NCT00207077
Completed
Phase 1
A Phase I Study of Cetuximab in Combination With Erlotinib in Patients With Advanced Solid Malignancies
Overview
- Phase
- Phase 1
- Intervention
- Cetuximab + Erlotinib
- Conditions
- Neoplasms
- Sponsor
- Eli Lilly and Company
- Enrollment
- 33
- Locations
- 1
- Primary Endpoint
- Safety and efficacy of the combination of Tarceva and Erbitux
- Status
- Completed
- Last Updated
- 10 years ago
Overview
Brief Summary
The purpose of this study is to find a safe and effective dose of the combination of cetuximab (Erbitux) and Tarceva (erlotinib).
Investigators
Eligibility Criteria
Inclusion Criteria
- •Measurable disease
- •Life expectancy of at least 3 months
- •Must have at least one prior chemotherapy containing a platinum
Exclusion Criteria
- •Known or documented brain metastases
- •Prior cetuximab therapy
Arms & Interventions
A
Intervention: Cetuximab + Erlotinib
Outcomes
Primary Outcomes
Safety and efficacy of the combination of Tarceva and Erbitux
Secondary Outcomes
- Radiographic response
Study Sites (1)
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