Correlation between Reflux Symptom Index, Reflux Finding Score and Voice Handicap Index-10 in patients of Laryngopharyngeal Reflux before and after treatment
试验速览
- 阶段
- 不适用
- 状态
- 尚未招募
- 发起方
- 入组人数
- 280
- 试验地点
- 1
- 主要终点
- To evaluate the correlation between Reflux Finding Score, Reflux Symptom Index and Voice Handicap Index-10
研究概览
简要总结
The study titled “Correlation between Reflux Symptom Index, Reflux Finding Score and Voice Handicap Index in Patients of Laryngopharyngeal Reflux Before and After Treatment” aims to evaluate and correlate clinical scoring systems—RSI, RFS, and VHI-10—for diagnosing and monitoring laryngopharyngeal reflux (LPR).
LPR is characterized by the backward flow of gastric contents into the laryngopharynx, leading to symptoms such as hoarseness, chronic cough, throat clearing, and globus sensation. Many patients with LPR do not experience typical gastroesophageal reflux symptoms, making diagnosis challenging.
The study’s primary objective is to determine the prevalence of LPR in patients presenting with throat-related complaints and to assess the correlation between RSI, RFS, and VHI-10 scores before and after treatment. It also aims to evaluate improvement in these scores after 2, 4, and 6 weeks of medical management.
Adult patients aged 18–60 years will undergo laryngoscopic examination and complete RSI and VHI-10 questionnaires. Patients with conditions like asthma, smoking history, vocal cord lesions, or systemic diseases are excluded.
By using simple, non-invasive scoring systems, the study intends to facilitate easier diagnosis, monitor treatment outcomes, and improve clinical care for patients with LPR.
研究设计
- 研究类型
- Observational
入排标准
- 年龄范围
- 18.00 Year(s) 至 60.00 Year(s)(—)
- 性别
- All
入选标准
- •Patients with throat symptoms willing for throat endoscopy and follow up Patients willing to give informed consent.
排除标准
- •Patients with history of previous gastric surgery, pregnancy, asthma or COPD or TB, Cerebrovascular accident, hypertension on calcium channel blockers, hypothyroidism, smokers or alcoholics Vocal cord polyp, nodule or growth Acute or chronic respiratory tract infections Patients with previous radiotherapy or head and neck surgeries or neck trauma Patients already on treatment for LPR/GERD/APD.
结局指标
主要结局
To evaluate the correlation between Reflux Finding Score, Reflux Symptom Index and Voice Handicap Index-10
时间窗: Once at the time of visit | 6 weeks
次要结局
- To assess the change in clinical scores following six weeks of treatment(Once after 6 weeks)
研究者
Dr Neha Agarwal
Varun Arjun Medical College and Rohilkhand Hospital
