MedPath

The effectiveness of ondansetron on pregnant wome

Phase 2
Conditions
pregnant women.
Other single delivery by caesarean section
Registration Number
IRCT2015102813159N7
Lead Sponsor
Vice Chancellor for Research, Mashhad University of Medical Sciences
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
Complete
Sex
Female
Target Recruitment
120
Inclusion Criteria

ASA I and ASA II diseases; aged between 18 and 40 years; single or twin gestations; undergoing Cesarean section or spinal anaesthesia for emergency Caesarean; not using anti-migraine therapeutics, SSRI or MAO inhibitors; not being allergic to ondansetron; absence of psychological disorders; and not consuming drugs or alcohol.
Exclusion criteria: Failure of spinal anesthesia; untreatable pain with 50 micrograms of fentanyl after the onset of surgery; bleeding more than expected (500 cc in single gestation and 1000 cc in twin gestations); numbness extending beyond the dermatome T4 level according to skin testing with needle point; need to expand incision during surgery due to the surgical complications; and having major complications during surgery.

Exclusion Criteria

Not provided

Study & Design

Study Type
interventional
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
Maternal blood pressure. Timepoint: Before and after anesthesia. Method of measurement: Clinical mercury Manometer; mmHg.
Secondary Outcome Measures
NameTimeMethod
Maternal heart rate. Timepoint: Before and after anesthesia. Method of measurement: Monitoring Compact; in minuets.
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