The analgesic efficacy of infiltration between the popliteal artery and capsule of the knee (IPACK) block when added to local infiltration analgesia and continuous adductor canal block after total knee arthroplasty: A randomized clinical trial

Not Applicable

Completed

• Conditions: Total Knee Arthroplasty; Popliteal plexus block; Adductor canal block; Local infiltration analgesia; Enhanced recovery; Opioid free analgesia; Total knee arthroplasty

• Registration Number: TCTR20180702001
• Lead Sponsor: none

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Start: 2018-07-02
• Study Completion: 2019-07-01
• Last Update Posted: 19 August 2024

Recruitment & Eligibility

• Status: Completed
• Sex: All
• Target Recruitment: 72

Inclusion Criteria

Patient who was scheduled for total knee arthroplasty at King Chulalongkorn Memorial Hospital ASA class 1 to 3

ASA class 1 A normal healthy patient
ASA class 2 A patient with mild systemic disease Mild diseases only without substantive functional limitations
ASA class 3 A patient with severe systemic disease but not threaten to life
Body mass index BMI between 18 to 40 kg m2

Exclusion Criteria

refuse to participate this study
unable to cooperate or cognitive impairment eg dementia
allergy to any drug in this study
contraindication to neuraxial anesthesia eg coagulopathy
contraindication to NSAIDs Ketorolac and Celebrex in this study
chronic opioids use or diagnosed of neuropathic pain
unable to performed Time up and go test

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Post operative opioid consumption 24 hours Milligram of Morphine Consumption

Secondary Outcome Measures

Name	Time	Method
Postoperative Pain Score 0, 4, 8, 12, 24, 36 and 48 hours, 2 and 5 days, 2 weeks, 6 weeks and 2 months Visual Analog Scale,Post operative opioid consumption 12, 48 hours Milligram of Morphine Consumption,Quadriceps Strength Postoperative 0, 1, 2, 3 Days and 3 Months Maximum voluntary isometric contraction,Cumulated Ambulation Score Postoperative 0, 1, 2, 3 Days Rehabilitation after surgery,Postoperative Complication Postoperative 0, 1, 2, 3 Days Postoperative Nausea Vomiting, Fall, Dizziness, Sleep disturbance, Timed up and go test Postoperative 3 Months Rehabilitation after surgery,Delta Timed up and go test Preoperative and 3 months after surgery Rehabilitation after surgery,Length of stays Postoperative to discharge out of hospital Days,Walking aid Postoperative 2 and 5 days, 2 weeks, 6 weeks and 2 months Rehabilitation after surgery