Evaluating the effectiveness of locally applied melatonin gel in the treatment of advanced gum disease.
Phase 2
- Conditions
- Health Condition 1: K052- Aggressive periodontitis
- Registration Number
- CTRI/2022/08/044750
- Lead Sponsor
- JSS Academy of Higher Education and Research
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- ot Yet Recruiting
- Sex
- Not specified
- Target Recruitment
- 0
Inclusion Criteria
Aged above 18 years
Willing to offer informed consent
Having severe periodontitis
Exclusion Criteria
With known history of allergy or hypersensitivity to the drugs in trial
Systemic diseases that compromise periodontal host defense mechanism
History of use of antimicrobial drugs in the last three months
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Clinical parameters like gingival index, probing pocket depth, clinical attachment loss, bleeding index and bone loss in test and control group will be assessed.Timepoint: Baseline, 6 weeks, 6 months
- Secondary Outcome Measures
Name Time Method Radiological parameters using CBCT/IOPA will be evaluated at baseline and six months following intervention.Timepoint: Baseline and six months following intervention.