Pectin Supplemented Enteral Feedings in Critically Ill Patients

Not Applicable

Withdrawn

• Conditions: Enteral Nutrition; Dietary Fiber
• Interventions: Other: enteral nutrition feeding; Dietary Supplement: pectin-supplemented enteral nutrition feeding

• Registration Number: NCT04438473
• Lead Sponsor: Second Affiliated Hospital, School of Medicine, Zhejiang University

Brief Summary

The current study will enroll critically ill patients who are going to require enteral nutrition support and randomize them to standard formula enteral nutrition or pectin-supplemented enteral nutrition in 7 days. The occurrence of enteral nutrition-related complications will be recorded and compared between groups.

The study is trying to assess whether the use of pectin will improve the enteral nutrition-related complications in critically ill patients.

Detailed Description

Not available

Study Timeline

• Study First Submitted: 2020-06-17
• Study First Submitted QC: 2020-06-17
• Study First Posted: 2020-06-18
• Study Start: 2020-07-30
• Primary Completion: 2020-12-01
• Status Verified: 2021-07
• Last Update Submitted: 2021-07-14
• Last Update Posted: 2021-07-15
• Study Completion: 2021-12-01

Recruitment & Eligibility

• Status: WITHDRAWN
• Sex: All
• Target Recruitment: Not specified

Inclusion Criteria

• Patients aged 18-80 years old, with informed consent to participate;
• Critically ill patients who require enteral nutrition support

Exclusion Criteria

• Patients with lung infection at admission
• Condition which contraindicates enteral feeding (i.e. intestinal obstruction)
• Lack of enteral access
• Any condition that would contraindicate use of the enteral nutrition
• Require enteral nutrition support for less than 1week or more than 4 weeks from enrollment

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
Control	enteral nutrition feeding	standard formula enteral nutrition feeding without pectin for 7 days
Pectin	pectin-supplemented enteral nutrition feeding	sequential supplementation with combination of 90ml pectin and 500ml enteral nutrition formula for 7 days

Primary Outcome Measures

Name	Time	Method
Complication of enteral feeding	7 days	Record daily diarrhea ,complications, aspiration pneumonia,poor gastric emptying

Secondary Outcome Measures

Name	Time	Method
feeding time of enteral nutrition	7 days	Record daily feeding time of enteral nutrition
total energy intake	7 days	Record daily energy intake

Trial Locations

Locations (7)

The Second Affiliated Hospital, Zhejiang University School of Medicine; 🇨🇳 Hangzhou, Zhejiang, China

Jinhua municipal central hospital; 🇨🇳 Jinhua, Zhejiang, China

Huzhou central hospital; 🇨🇳 Huzhou, Zhejiang, China

The first hospital of Jiaxing; 🇨🇳 Jiaxing, Zhejiang, China

Quzhou Kecheng People's Hospital; 🇨🇳 Quzhou, Zhejiang, China

Taizhou Hospital of Zhejiang Province; 🇨🇳 Taizhou, Zhejiang, China

The first affiliated hospital of Wenzhou medical university; 🇨🇳 Wenzhou, Zhejiang, China