Investigation of effective treatment of nocturnal hypertension in diabetes
Phase 4
- Conditions
- octurnal hypertension in type 2 DM
- Registration Number
- JPRN-UMIN000001802
- Lead Sponsor
- Kobe University Graduate School of Medicine Division of deabetes, metabolism and endocrinology
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete: follow-up complete
- Sex
- All
- Target Recruitment
- 50
Inclusion Criteria
Not provided
Exclusion Criteria
1) patients with secondary hypertension 2) patients with liver dysfunction (GPT over three times the normal value) 3) patients with renal failure (serum creatinine over 2.0 mg/dL) 4) patients with bilareral renal artery stenosis 5) pregnant or possible pregnant women 6) patients with a history of hypersensitivity to Losartan or thiazide
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Change in nocturnal blood pressure level after 12 weeks of treatment
- Secondary Outcome Measures
Name Time Method change in blood pressure level on an outpatient basis after 4,8 weeks of treatment change after12 weeks about HbA1c, fasting bllod glucose level, urine alubimin excretion, Urine Na, Crine K, renin, aldsterone, BNP, serum K, serum Na, serum UA, serum Creatinine, eGFR, LDL-C, TG, HDL-C