The Outcome of Various Methods of Surgical Reconstruction of Depressed Skull Fractures

Completed

• Conditions: Head Trauma Injury

• Registration Number: NCT06879028
• Lead Sponsor: Assiut University

Brief Summary

* To investigate the outcomes of different approaches to surgical repair/Elevation of Traumatic Depressed Skull Fractures

* To improve the outcome of surgical elevation of depressed fractures regarding the rate of post-operative deficit and complications, as well as the aesthetics and patient recovery

Detailed Description

Depressed Fractures are of the commonest conditions seen in Head injuries; its incidence is unknown, but it is seen most commonly in Assault by hard objects and Road Traffic Accidents (8) and other high momentum collisions with the skull. Parietal bone is the most commonly fractured, followed by Temporal, Occipital and Frontal bones (1,8) They are classified mainly as Simple (Closed) or Compound (Open). Depressed fractures can be managed conservatively (2,3) but surgical intervention is needed if the depression is greater than calvarium thickness (1,2,8) or the fracture is over the Superior Sagittal Sinus, or risk infection from external debris. (4,6) Depressed Fractures when associated with underlying intracranial pathology (Mostly Haematoma or contusions) (1,2,8) require surgical elevation and management of other complications.

Elevation and debridement is recommended as the surgical method of choice. All management strategies for compound depressed fractures should include antibiotics. (1,2,8) Paediatric populations have better outcome (3,7) due to possibility for future remodelling and cranial growth.

Safe and effective surgical techniques to elevate Depressed fractures include craniotomy, surgical elevation with primary replacement of bone fragments in place, elevation through a burr hole at the periphery, fixation of bone fragments with miniplates, or fixation of bone fragments with vicryl sutures.

However, no available studies signify a preferable approach to depressed fractures or outcome of different methods. So, our study will try to identify and establish a significant treatment plan and preferable approach.

1. Golfinos JG, Cooper PR. Skull fracture and post-traumatic cerebrospinal fluid fistula. In: Head Injury, 4th, Cooper PR, Golfinos JG (Eds), McGraw-Hill, New York 2000. p.155.

2. Bullock, M. R., Chesnut, R., Ghajar, J., Gordon, D., Hartl, R., Newell, D. W., ... Wilberger, J. (2006). Surgical Management of Depressed Cranial Fractures. Neurosurgery, 58(Supplement), S2-56-S2-60. doi:10.1227/01.neu.0000210367.14

3. Bonfield, C. M., Naran, S., Adetayo, O. A., Pollack, I. F., \& Losee, J. E. (2014). Pediatric skull fractures: the need for surgical intervention, characteristics, complications, and outcomes. Journal of Neurosurgery: Pediatrics, 14(2), 205-211. doi:10.3171/2014.5.peds13414

4. HESHAM EL-SOBKEY, M.D., Ph.D., A. F. K. M. P. Surgical Elevation for Symptomatic Depressed Skull Fractures Over Dural Venous Sinus. The Medical Journal of Cairo University, 2019; 87(June): 1917-1925. doi: 10.21608/mjcu.2019.54048

5. Nnadi MO, Bankole OB, Arigbabu SO. Outcome of surgically treated non-missile traumatic depressed skull fracture. Niger Postgrad Med J. 2014 Dec;21(4):311-4. PMID: 25633449.

6. Abdelaal, M., Saro, A., Fadl, K., Abdelrahman, A. Management of Compound Depressed Fractures Over Major Cranial Venous Sinuses. The Egyptian Journal of Hospital Medicine, 2021; 83(1): 1177-1182. doi: 10.21608/ejhm.2021.161776

7. Al-Haddad SA, Kirollos R. A 5-year study of the outcome of surgically treated depressed skull fractures. Ann R Coll Surg Engl. 2002 May;84(3):196-200. PMID: 12092875; PMCID: PMC2503833.

8. Prakash A, Harsh V, Gupta U, Kumar J, Kumar A. Depressed Fractures of Skull: An Institutional Series of 453 Patients and Brief Review of Literature. Asian J Neurosurg. 2018 Apr-Jun;13(2):222-226. doi: 10.4103/ajns.AJNS_168_16. PMID: 29682012; PMCID: PMC5898083.

Study Timeline

• Study Start: 2023-10-01
• Primary Completion: 2024-10-01
• Study Completion: 2024-10-01
• Status Verified: 2025-03
• Study First Submitted: 2025-03-11
• Study First Submitted QC: 2025-03-11
• Last Update Submitted: 2025-03-11
• Study First Posted: 2025-03-17
• Last Update Posted: 2025-03-17

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 60

Inclusion Criteria

Not provided

Exclusion Criteria

Not provided

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Rates of Surgical Sites infection	6 months
Cosmosis and Post Op Appearance	6 months

Trial Locations

Locations (1)

Assiut University Hospitals; 🇪🇬 Assiut, Egypt