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Clinical Trials/NCT02071784
NCT02071784
Completed
Not Applicable

Etude Comparative en Imagerie Par résonnance magnétique et Par Enregistrement électroencéphalographique du Couplage Neurovasculaire Dans l'Angiopathie Cadasil

Institut National de la Santé Et de la Recherche Médicale, France1 site in 1 country60 target enrollmentJuly 8, 2014
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ConditionsCADASIL

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
CADASIL
Sponsor
Institut National de la Santé Et de la Recherche Médicale, France
Enrollment
60
Locations
1
Primary Endpoint
model-derived parameters of neurovascular coupling
Status
Completed
Last Updated
last month
OverviewInvestigatorsEligibility CriteriaOutcomesSitesSimilar Trials

Overview

Brief Summary

The aim of this study is to investigate using fMRI methods, EEG and dedicated mathematical models, the potential alterations of neurovascular coupling in CADASIL.

Detailed Description

Comparison study of parameters derived from mathematical models of neurovascular coupling and obtained using fMRI (Bold signal, ASL and EEG).

Registry
clinicaltrials.gov
Start Date
July 8, 2014
End Date
October 24, 2016
Last Updated
last month
Study Type
Observational
Sex
All

Investigators

Sponsor
Institut National de la Santé Et de la Recherche Médicale, France
Responsible Party
Sponsor

Eligibility Criteria

Inclusion Criteria

  • •CADASIL group: typical NOTCH3 mutation, age less than 60 years, rankin score at 0-1, active social insurance

Exclusion Criteria

  • •MRI contra-indications and use of any treatment known to interfere with neurovascular coupling, pregnancy, lack of informed consent

Outcomes

Primary Outcomes

model-derived parameters of neurovascular coupling

Time Frame: one time point

Study Sites (1)

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