Behavioral Interventions to Reduce Particulate Matter Exposure in Patients With COPD
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 120
- 试验地点
- 1
- 主要终点
- CAT
研究概览
简要总结
It is a prospective, multi-institutional clinical study and targets patients diagnosed with chronic obstructive pulmonary disease. About 120 subjects (35 at Ilsan Paik Hospital, 35 at Severance Hospital, and 50 at Asan Medical Center in Seoul) will be subject to a random allocation of 1:1. The arbitration group implements living rules for responding to fine dust, supports air purifiers, and only general guidance is implemented in the non-property group. Patients are recruited from Asan Medical Center in Seoul (Songpa-gu, Seoul), Severance Hospital ( Seodaemun-gu, Seoul), and Ilsan Paik Medical Center (Goyang, Gyeonggi-do) for 12 months. During outpatient visits, lung function tests and airway resistance tests shall be conducted, and surveys presented in the research plan shall be conducted.
详细描述
It is a prospective and multi-institutional clinical study targeting patients with chronic obstructive pulmonary disease in general.
A total of 120 COPD patients will be recruited from three institutions: Asan Medical Center, Severance Hospital, and Ilsan Paik Hospital. (60/30/30 expected) A panel of COPD patients is established to conduct prospective studies, and measures to mediate recurrence and deterioration of adult chronic respiratory diseases due to exposure to fine dust are presented. Improvement of the lifestyle of the arbitration forces. Detailed research methods such as air purifier support are presented in the research plan.
In addition, a fine dust measurement researcher visits each household to measure indoor fine dust concentration. The measurement method of fine dust concentration will be using the process test method, IoT-based sensors, and direct-to-read measuring devices to measure Air Korea's air pollution. Detailed visit timing and methods are carried out in the manner specified in the research plan.
We collect sputum at every visit and blood at the last visit.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Basic Science
- 盲法
- Double (Investigator, Outcomes Assessor)
入排标准
- 年龄范围
- 40 Years 至 80 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •40 years of age or older
- •Waste function test results show FEV1/FVC<0.7, FEV1 <80% of forecast
排除标准
- •Patients under 18 years of age with changes in medication (such as inhalants).
- •Older people over 80 years of age.
- •People with no respiratory symptoms with mMRC
- •Who doesn't understand a simple explanation for fine dust exposure devices.
- •Someone who disagrees with the study.
研究组 & 干预措施
COPD_E
COPD patients with intervention
干预措施: Five active practices of living rules for responding to fine dust. (Behavioral)
COPD_C
COPD patients without intervention
结局指标
主要结局
CAT
时间窗: 12 months
Quality of life
SGRQ-C
时间窗: 12 months
Quality of life
次要结局
未报告次要终点
研究者
Sei Won Lee
associate professor
Asan Medical Center