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Phase II trial of chemoradiotherapy concurrent with S-1 plus cisplatin in patients with unresectable locally advanced squamous cell carcinoma of the head and neck (JCOG0706)

Phase 2
Conditions
unresectable locally advanced squamous cell carcinoma of the head and neck
Registration Number
JPRN-UMIN000001272
Lead Sponsor
Japan Clinical Oncology Group (JCOG)
Brief Summary

See the datails via "URL releasing results" above. Also the details can be seen in the JCOG website: http://www.jcog.jp/en/trials/index.html

Detailed Description

Not available

Recruitment & Eligibility

Status
Complete: follow-up complete
Sex
All
Target Recruitment
45
Inclusion Criteria

Not provided

Exclusion Criteria

1) Active bacterial or fungous infection 2) Simultaneous or metachronous (within 5 years) double cancers except carcinoma in situ or intramucosal tumor. 3) Pregnant or lactating women or women of childbearing potential 4) Active gastrointestinal bleeding 5) Pleural effusion, pericardial effusion, or severe ascites 6) History of severe heart disease, heart failure, myocardial infarction within 6 months or attack of angina pectoris within 6 months. 7) Cerebrovascular disease within 6 months 8) Uncontrollable diabetes mellitus or requiring administration of insulin 9) Uncontrollable hypertension 10) Chronic pancreatitis 11) Positive HBs antigen 12) Impossible to refrain from smoking and drinking during treatment 13) Requiring systemic steroids medication

Study & Design

Study Type
Interventional
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
Secondary Outcome Measures
NameTimeMethod
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