Influence of interdialytic weight gain, oxidative stress, and inflammation on hospitalization rate and mortality in maintenance hemodialysis individuals
Not Applicable
- Conditions
- Health Condition 1: N00-N99- Diseases of the genitourinary system
- Registration Number
- CTRI/2022/06/043472
- Lead Sponsor
- Kasturba Medical college Manipal
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- ot Yet Recruiting
- Sex
- Not specified
- Target Recruitment
- 0
Inclusion Criteria
All stable individuals who are undergoing maintenance hemodialysis
Exclusion Criteria
Post-transplant patients with graft failure
Patients on other dialysis modalities
Patients with malignancy
Patients with liver disease
Patients with chronic inflammatory disorders (Tuberculosis, rheumatoid arthritis vasculitis)
Patients with active infections/ hospitalization 3 months before enrolment
HIV, HCV, and HbsAg positive patients
Patients taking or have received anti-oxidants, steroids, and immunosuppressive medications in the last 6 months
Pregnancy
Study & Design
- Study Type
- Observational
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method 1. Quantity of interdialytic fluid gain, oxidative stress, and inflammation in maintenance hemodialysis individuals and evidence for their impact on hospitalization rate and mortality <br/ ><br>2. Relationship between interdialytic fluid gain, oxidative stress, and inflammation <br/ ><br>Timepoint: One year six months <br/ ><br>
- Secondary Outcome Measures
Name Time Method 1. Relationship of interdialytic fluid gain, oxidative stress, and inflammation with Renal anemia <br/ ><br>2. Relationship between oxidative stress and mineral bone disease <br/ ><br>Timepoint: One year six months