跳至主要内容
临床试验/NCT05570890
NCT05570890Unknown不适用

Immediate Effect of Electrical Noise Stimulation on Neuromuscular Adaptation During Single-Leg Stance in Healthy Young

National Yang Ming Chiao Tung University2 个研究点 分布在 1 个国家目标入组 20 人开始时间: 2022年4月29日最近更新:
适应症

试验速览

阶段
不适用
入组人数
20
试验地点
2
主要终点
Mean sway velocity of the center of pressure

研究概览

简要总结

Noise stimulation had an immediate effect on improving balance control. The present study aimed to clarify the immediate neuromuscular adaptation induced by noise stimulation and find the correlation between neuromuscular adaptation and functional performance.

详细描述

The mechanism behind noise stimulation is called Stochastic Resonance which improves the detectivity of sensory input with the presence of noise, making sub-sensory threshold input detectable. Noise stimulation had been proved to improve postural control, Ia afferent sensitivity, and muscle activity of the tibialis anterior. With this evidence of the effect of noise stimulation on balance enhancement, the neuromuscular adaptation induced by noise stimulation has not been researched yet. Therefore, the present study aims to clarify the immediate effect of noise on neuromuscular regulation during postural control.

研究设计

研究类型
Interventional
分配方式
Randomized
干预模型
Parallel
主要目的
Basic Science
盲法
Single (Participant)

盲法说明

The stimulation intensity is set under the sensory threshold, therefore participants will be masked in the study.

入排标准

年龄范围
20 Years 至 40 Years(Adult)
性别
All
接受健康志愿者

入选标准

  • age between 20 and 40 years old
  • without ankle injury history in 1 year
  • without musculoskeletal or neurological diseases that would affect balance performance
  • without visual impairment (except vision correction or no visual problems)
  • without vestibular impairment.

排除标准

  • subject who cannot tolerate the cutaneous electrical stimulation to induce H reflex
  • single-leg stance (SLS) without support is shorter than 80 secs

结局指标

主要结局

Mean sway velocity of the center of pressure

时间窗: 40 seconds under each condition

The mean sway velocity in mm/sec will represent balance performance

Co-activation index

时间窗: 40 seconds after each condition

Co-activation index will be calculated by EMG activity of Tibialis Anterior and Soleus muscle to represent the muscle activity.

Mean sway path of the center of pressure

时间窗: 40 seconds under each condition

The mean sway path in mm will represent balance performance

Cortical excitability

时间窗: 40 seconds under each condition

Power spectrum density of EEG will calculated for representing cortical excitability.

Spinal reflex excitability

时间窗: 40 seconds under each condition

H reflex amplitude will represent the excitability of peripheral control from spinal level nerve system.

次要结局

未报告次要终点

研究者

申办方类型
Other
责任方
Sponsor

研究点 (2)

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