Tranexamic Acid in Preventing Postpartum Hemorrhage in High Risk Pregnancies During Elective Cesarean Section

Phase 2

Completed

• Conditions: Postpartum Hemorrhage
• Interventions: Drug: Tranexamic Acid

• Registration Number: NCT03351686
• Lead Sponsor: Mansoura University

Brief Summary

postpartum hemorrhage (PPT) represents one of the major causes of maternal mortality . Tranexamic acid is used in many studies in management of PPH in combination with ecobolics. this study aims to evaluate the possible value of the use of tranexamic acid in prevention of postpartum hemorrhage .

Detailed Description

Not available

Study Timeline

• Study Start: 2016-08-01
• Primary Completion: 2017-04-15
• Study Completion: 2017-04-15
• Status Verified: 2017-11
• Study First Submitted: 2017-11-20
• Study First Submitted QC: 2017-11-20
• Last Update Submitted: 2017-11-22
• Study First Posted: 2017-11-24
• Last Update Posted: 2017-11-27

Recruitment & Eligibility

• Status: COMPLETED
• Sex: Female
• Target Recruitment: 140

Inclusion Criteria

• Gestational age of 28 weeks or more.
• Chronic Hypertension.
• Preeclapmsia -Eclampsia.
• Multiple pregnancy.
• Uterine Liomyomas.
• Polyhydraminos.
• Fetal macrosomia.
• Associated Thrombocytopenia
• History of postpartum hemorrhage.

Exclusion Criteria

• Patients with rheumatic heart disease.
• Patients with history Cardiac Valve Replacement.
• Current or past history of DVT.
• Women on any anticoagulant therapy.
• Sensitivity to tranexamic acid
• Pregnancies with any abnormally implanted or located placenta.

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
tranexamic acid group	Tranexamic Acid	-

Primary Outcome Measures

Name	Time	Method
prevention of postpartum hemorrhage in high risk group	intraoperative	assessment of intraoperative blood loss