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Clinical Trials/NCT01610323
NCT01610323
Completed
Not Applicable

Fitness Improvement in Obese, Pregnant Women: an Intervention Trial (InterGOFIT)

CHU de Quebec-Universite Laval1 site in 1 country50 target enrollmentOctober 2011

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
Pregnancy
Sponsor
CHU de Quebec-Universite Laval
Enrollment
50
Locations
1
Primary Endpoint
Weekly time spent at physical activity of moderate intensity and above
Status
Completed
Last Updated
11 years ago

Overview

Brief Summary

In pregnancy, the adoption or pursuit of a sedentary lifestyle contributes to the development of co-morbid conditions such as hypertension, maternal and childhood obesity, gestational diabetes, pre-eclampsia, cesarean section and delivery of large-for-gestational-age infants (LGA).

The aim of this study is to test the hypothesis that obese, pregnant women following a supervised moderate intensity physical conditioning program during the 2nd trimester of pregnancy will maintain a higher level of physical activity up to the end of pregnancy, as compared to women in the control group. We will also conduct a pilot study on the feasibility to examine the effects of the intervention on maternal fitness and neonatal anthropometry.

Detailed Description

Looking at the multiple needs of pregnant women with obesity, physical conditioning may offer a great opportunity to improve fitness and to decrease cardio-metabolic disturbances, to prevent excessive weight gain, to improve general health status, and to reduce health care utilization. Furthermore, beneficial effects of fitness on adverse maternal health outcomes related to obesity might decrease the development of long-term obesity and metabolic repercussions in the offspring. The Society of Obstetricians and Gynaecologists of Canada (SOGC) recommends that all women without contraindication be encouraged to participate in aerobic and strength-conditioning exercises as part of a healthy lifestyle during pregnancy. Despite these recommendations, obese women are inactive during pregnancy and are currently still at high risk of poor physical fitness. Thus, although exercise clearly improves maternal health status and thus potentially prevents adverse perinatal outcomes, obese pregnant women poorly adhere to experts' recommendations about the need for exercise during pregnancy. Therefore, this situation justifies the need to develop adapted strategies aimed at increasing the implementation of guideline recommendations in this population.

Registry
clinicaltrials.gov
Start Date
October 2011
End Date
July 2014
Last Updated
11 years ago
Study Type
Interventional
Study Design
Parallel
Sex
Female

Investigators

Sponsor
CHU de Quebec-Universite Laval
Responsible Party
Sponsor

Eligibility Criteria

Inclusion Criteria

  • pregnant women 18 years or older
  • single pregnancy
  • delivery at Centre Hospitalier Universitaire de Québec
  • pre-pregnancy BMI ≥30 kg/m2

Exclusion Criteria

  • multiple pregnancy
  • diabetes or chronic hypertension prior to pregnancy
  • uncontrolled thyroid problems
  • exercise contraindications

Outcomes

Primary Outcomes

Weekly time spent at physical activity of moderate intensity and above

Time Frame: At 36 weeks of gestation

Accelerometry data (minutes per week spent over selected cutpoints)

Secondary Outcomes

  • Gestational weight gain(At 36 weeks of gestation)
  • Muscular fitness(At 28 wks of gestation)
  • Cardiorespiratory fitness(At 28 weeks of gestation)
  • Energy Expenditure(At 36 weeks of gestation)
  • Neonatal anthropometry(At delivery)
  • Fetal growth(At 28 weeks of gestation)

Study Sites (1)

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